Mouse anti-Human Chorionic Gonadotropin, beta Monoclonal Antibody | anti-CGB8 antibody

Chorionic Gonadotropin, Human, beta (hCGb)

Cat. Num. AAA631988

• Reactivity: Human
• Applications: ELISA
• Purity: Affinity Purified; Purified by Protein A affinity chromatography. 90% by SDS-PAGE.
• Synonyms: Chorionic Gonadotropin; beta; Monoclonal Antibody; Human; beta (hCGb); Anti -Chorionic Gonadotropin; anti-CGB8 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG1,k
• Clone Number: 4A95
• Specificity: When tested by ELISA, this antibody is specific for intact-HCG and its Beta subunit. No reactivity is observed with the Alpha subunit of HCG.
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography. 90% by SDS-PAGE.
• Form/Format: Supplied as a liquid in 10mM phosphate, pH 7.4, 150mM sodium chloride and 0.1% sodium azide.

• Applicable Applications for anti-CGB8 antibody: ELISA (EL/EIA)
• Application Notes: Suitable for use in ELISA.
• Immunogen: Human Chorionic Gonadotropin isolated from Human Pregnancy Urine
• Affinity Constant: 2.0 x 10e11L/M
• Preparation and Storage: May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Related Product Information for anti-CGB8 antibody

Human Chorionic Gonadotropin (HCG) is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the a-and b-subunits. The a-subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP), and HCG but negative for EMA and AFP is probably a choriocarcinoma.

Product Categories/Family for anti-CGB8 antibody

Antibodies; Abs to Hormones; Steroids

NCBI and Uniprot Product Information

• NCBI GI #: 15426252
• NCBI GeneID: 94115
• NCBI Accession #: NP_149439.1
• NCBI GenBank Nucleotide #: NM_033183.2
• NCBI Official Full Name: chorionic gonadotropin, beta polypeptide 8
• NCBI Official Synonym Full Names: chorionic gonadotropin, beta polypeptide 8
• NCBI Official Symbol: CGB8
• NCBI Protein Information: chorionic gonadotropin, beta polypeptide 8; chorionic gonadotropin beta 8 subunit

NCBI Description

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 8 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq, Jul 2008]