Mouse Cholera Toxin Monoclonal Antibody | anti-ctxB antibody
Anti-Cholera Toxin (mouse monoclonal), coating
Applications
Western Blot, ELISA
Purity
Chromatography on protein A Sepharose
Synonyms
Cholera Toxin; Monoclonal Antibody; Anti-Cholera Toxin (mouse monoclonal); coating; Anti-Cholera Toxin (beta-Subunit) Mouse Monoclonal Antibody; anti-ctxB antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
B8
Specificity
React with cholera toxin
Purity/Purification
Chromatography on protein A Sepharose
Concentration
1 mug/mul in PBS pH7.4, 0.1% sodium azide (varies by lot)
Sequence Length
124
Applicable Applications for anti-ctxB antibody
Western Blot (WB), ELISA (EIA), Sandwich Immunoassay
Application Notes
EIA (coating), B-subunit of CT
Usage
This product does not contain livestock or poultry disease agents, non-toxic/non contagious and is not intended for human use, only for laboratory research and development.
Immunogen
Purified beta-subunit of cholera toxin
Preparation and Storage
Store at -20 degree C. Stable for at least 1 month from the date of shipment at 4 degree C.
Related Product Information for anti-ctxB antibody
Description: Anti-Cholera Toxin B Subunit
Mouse anti-cholera toxin (beta-subunit) monoclonal antibody
Introduction: Cholera toxin is a protein complex secreted by the bacterium Vibrio cholerae. The cholera toxin is an oligomeric complex made up of six protein subunits: a single copy of the A subunit (part A, enzymatic), and five copies of the B subunit (part B, receptor binding), denoted as AB5. B subunits bind and internalize A subunits, which are processed to A1. The A1 form catalyses ADP ribosylation from NAD to the regulatory component of adenylate cyclase, thereby activating it. Increased adenylate cyclase activity increases cyclic AMP (cAMP) synthesis causing massive fluid and electrolyte efflux, resulting in diarrhoea.
Mouse anti-cholera toxin (beta-subunit) monoclonal antibody
Introduction: Cholera toxin is a protein complex secreted by the bacterium Vibrio cholerae. The cholera toxin is an oligomeric complex made up of six protein subunits: a single copy of the A subunit (part A, enzymatic), and five copies of the B subunit (part B, receptor binding), denoted as AB5. B subunits bind and internalize A subunits, which are processed to A1. The A1 form catalyses ADP ribosylation from NAD to the regulatory component of adenylate cyclase, thereby activating it. Increased adenylate cyclase activity increases cyclic AMP (cAMP) synthesis causing massive fluid and electrolyte efflux, resulting in diarrhoea.
Product Categories/Family for anti-ctxB antibody
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
13,957 Da
NCBI Official Full Name
cholera toxin
UniProt Protein Name
Cholera enterotoxin subunit B
Protein Family
UniProt Gene Name
ctxB
UniProt Entry Name
CHTB_VIBCH
Uniprot Description
The B subunit pentameric ring directs the A subunit to its target by binding to the GM1 gangliosides present on the surface of the intestinal epithelial cells. It can bind five GM1 gangliosides. It has no toxic activity by itself.
Similar Products
Product Notes
The Cholera Toxin ctxb (Catalog #AAA430005) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Cholera Toxin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Sandwich Immunoassay. EIA (coating), B-subunit of CT. Researchers should empirically determine the suitability of the Cholera Toxin ctxb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cholera Toxin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
