Mouse Chemotaxis Inhibiting Protein of Staphylococcus aureus Monoclonal Antibody | anti-SA1755 antibody

Chemotaxis Inhibiting Protein of Staphylococcus aureus, NT (CHIPS)

Cat. Num. AAA608060

• Applications: Western Blot, Immunohistochemistry, Flow Cytometry, Functional Assay
• Purity: Affinity Purified; Purified
• Synonyms: Chemotaxis Inhibiting Protein of Staphylococcus aureus; Monoclonal Antibody; NT (CHIPS); Anti -Chemotaxis Inhibiting Protein of Staphylococcus aureus; anti-SA1755 antibody

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG1
• Clone Number: 9G167
• Specificity: Recognizes the N-terminus of CHIPS.
• Purity/Purification: Affinity Purified; Purified
• Form/Format: Supplied as a liquid in PBS, 0.1% BSA, 0.02% sodium azide.

• Applicable Applications for anti-SA1755 antibody: Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
• Application Notes: Suitable for use in Flow Cytometry, Western Blot, Immunoassays, Immunohistochemistry.; Dilution: Flow Cytometry: 1:10; Western Blot: 1:100; Immunohistochemistry (frozen and paraffin): 1:100 Before use in biological assays, the product must be filter sterilized and depending on the concentration to be used dialyzed against culture medium to remove the sodium azide added.
• Immunogen: Chemotaxis Inhibiting Protein of Staphylococcus aureus.
• Preparation and Storage: May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Related Product Information for anti-SA1755 antibody

The bacterial pathogen Staphylococcus aureus is insensitive to antimicrobial host defense peptides such as defensins, protegrins, platelet microbicidal proteins and bacteriocins. Staphylococci have developed various resistance mechanisms including those specific for bacteriocins and several host defense peptides. A protein belonging to the resistance mechanism of Staphylococcus aureus is known as CHIPS (Chemotaxis Inhibiting Protein of

Product Categories/Family for anti-SA1755 antibody

Antibodies; Abs to Infectious Disease Staph

NCBI and Uniprot Product Information

• NCBI GI #: 15927517
• NCBI GeneID: 1124642
• NCBI Accession #: NP_375050.1
• NCBI GenBank Nucleotide #: NC_002745.2
• UniProt Accession #: Q99SU8
• Molecular Weight: 17,073 Da
• NCBI Official Full Name: chemotaxis-inhibiting protein CHIPS
• NCBI Official Symbol: SA1755
• NCBI Protein Information: chemotaxis-inhibiting protein CHIPS
• UniProt Protein Name: Chemotaxis inhibitory protein
• UniProt Gene Name: chp
• UniProt Entry Name: CHIPS_STAAN

Uniprot Description

Function: Involved in countering the first line of host defense mechanisms. Specifically inhibits the response of human neutrophils and monocytes to complement anaphylatoxin C5a and formylated peptides, like N-formyl-methionyl-leucyl-phenylalanine (fMLP). Acts by binding directly to the C5a receptor (C5aR) and formylated peptide receptor (FPR), thereby blocking the C5a- and fMLP-induced calcium responses. Prevents phagocytosis of the bacterium

Subcellular location: Secreted

Sequence similarities: Belongs to the CHIPS/FLIPr family.