CHO cells anti-Human Certolizumab Monoclonal Antibody
Certolizumab
Reactivity
Human
Purity
>95%
Synonyms
Certolizumab; Monoclonal Antibody; TNF (DIF; TNF-alpha; TNFA; TNFSF2; cachexin; cachectin; TNFalpha) [Homo sapiens]; anti-Certolizumab antibody
Host
CHO cells
Reactivity
Human
Clonality
Monoclonal
Isotype
Fab-IgG1
Purity/Purification
>95%
Form/Format
Liquid. Supplied as solution form in PBS pH 7.4.
Concentration
3.16 mg/ml (varies by lot)
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Store at -80 degree C
Related Product Information for anti-Certolizumab antibody
Tumor necrosis factor alpha (TNFalpha) is a cytokine produced primarily by monocytes and macrophages. It is found in synovial cells and macrophages in the tissues. The primary role of TNFalpha is in the regulation of immune cells. TNFalpha is able to induce apoptotic cell death, to induce inflammation, and to inhibit tumorigenesis and viral replication. Dysregulation of TNFalpha production has been implicated in a variety of human diseases, including major depression, Alzheimer's disease and cancer. Recombinant TNFalpha is used as an immunostimulant under the INN tasonermin. TNFalpha can be produced ectopically in the setting of malignancy and parallels parathyroid hormone both in causing secondary hypercalcemia and in the cancers with which excessive production is associated.
Product Categories/Family for anti-Certolizumab antibody
References
1. Corbett M, Chehadah F, Biswas M, Moe-Byrne T, Palmer S, Soares M, Walton M, Harden M, Ho P, Woolacott N, Bojke L: Certolizumab pegol and secukinumab for treating active psoriatic arthritis following inadequate response to disease-modifying antirheumatic drugs: a systematic review and economic evaluation. Health Technol Assess. 2017 Oct;21 (56) :1-326. doi: 10.3310/hta21560. [PubMed:28976302]
Similar Products
Product Notes
The Certolizumab (Catalog #AAA156715) is an Antibody produced from CHO cells and is intended for research purposes only. The product is available for immediate purchase. The Certolizumab reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Certolizumab, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
