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Western Blot (WB) (Western blot detection of CDX2 in Hela, Caco2, C2C12, SW480, COS7, HepG2 and 3T3 cell lysates using CDX2 mouse mAb (1:1000 diluted).Predicted band size:34KDa.Observed band size:34KDa.)

CDX2 Monoclonal Antibody | anti-CDX2 antibody

Anti-CDX2 Mouse mAb

Gene Names
CDX2; CDX3; CDX-3; CDX2/AS
Reactivity
Human, Monkey, Mouse
Applications
Western Blot, Immunoprecipitation, Immunocytochemistry
Purity
Affinity Purified
Synonyms
CDX2; Monoclonal Antibody; Anti-CDX2 Mouse mAb; Caudal type homeo box 2; Caudal type homeo box transcription factor 2; Caudal type homeobox 2; Caudal type homeobox protein 2; caudal type homeobox transcription factor 2; Caudal-type homeobox protein 2; CDX 2; CDX 3; CDX-3; Cdx2; CDX2_HUMAN; CDX3; Homeobox protein CDX 2; Homeobox protein CDX-2; Homeobox protein CDX2; anti-CDX2 antibody
Ordering
For Research Use Only!
Host
Mouse
Source: Human
Reactivity
Human, Monkey, Mouse
Clonality
Monoclonal
Isotype
lgG2b
Clone Number
4B9-B12-E9
Purity/Purification
Affinity Purified
Form/Format
Purified mouse monoclonal in PBS (pH 7.4)containing with 0.2% sodium azide, 50% glycerol.
Concentration
1.5mg/ml (varies by lot)
Sequence Length
313
Applicable Applications for anti-CDX2 antibody
Western Blot (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)
Application Notes
WB: 1:1000
ICC: 1:100
Immunogen
Purified recombinant human CDX2 protein fragments expressed in E Coli
Sensitivity
This antibody detects endogenous levels of CDX2 and does not cross-react with related proteins.
Sequence Similarities
Belongs to the Caudal homeobox family.Contains 1 homeobox DNA-binding domain.
Subcellular Location
Nucleus

Western Blot (WB)

(Western blot detection of CDX2 in Hela, Caco2, C2C12, SW480, COS7, HepG2 and 3T3 cell lysates using CDX2 mouse mAb (1:1000 diluted).Predicted band size:34KDa.Observed band size:34KDa.)

Western Blot (WB) (Western blot detection of CDX2 in Hela, Caco2, C2C12, SW480, COS7, HepG2 and 3T3 cell lysates using CDX2 mouse mAb (1:1000 diluted).Predicted band size:34KDa.Observed band size:34KDa.)

Immunocytochemistry (ICC)

(Immunocytochemistry stain of Hela using CDX2 mouse mAb (1:100).)

Immunocytochemistry (ICC) (Immunocytochemistry stain of Hela using CDX2 mouse mAb (1:100).)

Immunoprecipitation (IP)

(Immunoprecipitation analysis of Hela cell lysate using CDX2 mouse mAb.)

Immunoprecipitation (IP) (Immunoprecipitation analysis of Hela cell lysate using CDX2 mouse mAb.)
Related Product Information for anti-CDX2 antibody
Entrez Summary: This gene is a member of the caudal-related homeobox transcription factor gene family.The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation.This protein also plays a role in early embryonic development of the intestinal tract.Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis.[provided by RefSeq, Jan 2012]
UniPort Summary Function: Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium.Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
34
NCBI Official Full Name
homeobox protein CDX-2
NCBI Official Synonym Full Names
caudal type homeobox 2
NCBI Official Symbol
CDX2
NCBI Official Synonym Symbols
CDX3; CDX-3; CDX2/AS
NCBI Protein Information
homeobox protein CDX-2
UniProt Protein Name
Homeobox protein CDX-2
Protein Family
UniProt Gene Name
CDX2
UniProt Synonym Gene Names
CDX3

NCBI Description

This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis. [provided by RefSeq, Jan 2012]

Uniprot Description

CDX2: Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine. Belongs to the Caudal homeobox family.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 13q12.2

Cellular Component: nucleoplasm; nucleus

Molecular Function: transcription factor activity

Biological Process: anterior/posterior axis specification; cell differentiation; negative regulation of transcription from RNA polymerase II promoter; organ morphogenesis; regulation of somitogenesis; transcription from RNA polymerase II promoter

Research Articles on CDX2

Similar Products

Product Notes

The CDX2 cdx2 (Catalog #AAA475024) is an Antibody produced from Mouse Source: Human and is intended for research purposes only. The product is available for immediate purchase. The Anti-CDX2 Mouse mAb reacts with Human, Monkey, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CDX2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC). WB: 1:1000 ICC: 1:100. Researchers should empirically determine the suitability of the CDX2 cdx2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CDX2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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