Mouse anti-Human CD96 Monoclonal Antibody | anti-CD96 antibody

CD96 (T-cell Surface Protein Tactile, Cell Surface Antigen CD96, T Cell-activated Increased Late Expression Protein) (MaxLight 405)

Cat. Num. AAA6189347

• Gene Names: CD96; TACTILE
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: CD96; Monoclonal Antibody; CD96 (T-cell Surface Protein Tactile; Cell Surface Antigen CD96; T Cell-activated Increased Late Expression Protein) (MaxLight 405); anti-CD96 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG2a,k
• Clone Number: 3H8
• Specificity: Recognizes human CD96.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight405.

• Applicable Applications for anti-CD96 antibody: FLISA, Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length recombinant protein corresponding to aa1-402 from CD96 (AAH20749; BC020749) with GST tag. MW of the GST tag alone is 26kD.
• Immunogen Sequence: MEKKWKYCAVYYIIQIHFVKGVWEKTVNTEENVYATLGSDVNLTCQTQTVGFFVQMQWSKVTNKIDLIAVYHPQYGFYCAYGRPCESLVTFTETPENGSRWTLHLRNMSCSVSGRYECMLVLYPEGIQTKIYNLLIQTHVTADEWNSNHTIEIEINQTLEIPCFQNSSSKISSEFTYAWSVEDNGTQETLISQNHLISNSTLLKDRVKLGTDYRLHLSPVQIFDDGRKFSCHIRVGPNKILRSSTTVKVFAKPEIPVIVENNSTDVLVERRFTCLLKNVFPKANITWFIDGSFLHDEKEGIYITNEERKGKDGFLELKSVLTRVHSNKPAQSDNLTIWCMALSPVPGNKVWNISSGKITFLLGSEISSTDPPLSVTESTLDTQPSPASSVSPASKNVFTLSY
• Conjugate: MaxLight405
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight405 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western Blot detection against Immunogen (70.33kD).)

Testing Data

(Detection limit for recombinant GST tagged CD96 is ~3ng/ml as a capture antibody.)

Related Product Information for anti-CD96 antibody

CD96 promotes natural killer (NK) cell adhesion to target cells expressing the poliovirus receptor (PVR or CD155). Furthermore CD96 stimulates cytotoxicity of activated NK cells, and mediates acquisition of PVR from target cells. This means NK cells have due to the receptor CD96 a dual receptor system that recognizes nectins and nectin-like molecules on target cells and mediates NK cells adhesion and triggering of effector functions. As PVR is highly expressed in certain tumors, this receptor system may be critical for NK cell recognition of tumors.

Product Categories/Family for anti-CD96 antibody

Antibodies; CD Markers

NCBI and Uniprot Product Information

• NCBI GI #: 18088449
• NCBI GeneID: 10225
• Molecular Weight: 63,888 Da
• NCBI Official Full Name: Homo sapiens CD96 molecule, mRNA
• NCBI Official Synonym Full Names: CD96 molecule
• NCBI Official Symbol: CD96
• NCBI Official Synonym Symbols: TACTILE
• NCBI Protein Information: T-cell surface protein tactile
• Protein Family: T-cell surface protein tactile

NCBI Description

The protein encoded by this gene belongs to the immunoglobulin superfamily. It is a type I membrane protein. The protein may play a role in the adhesive interactions of activated T and NK cells during the late phase of the immune response. It may also function in antigen presentation. Alternative splicing generates multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2016]