Testing Data
(Figure A. RPE conjugated rat anti mouse CD4 . Figure B. RPE conjugated rat anti mouse CD4 and A488 conjugated mouse anti mouse CD90 . All experiments performed on red cell lysed murine splenocytes gated on mononuclear cells. Data acquired on the ZE5 cell analyzer.)
Mouse anti-Mouse CD90 Monoclonal Antibody | anti-CD90 antibody
Mouse Anti Mouse CD90: RPE
This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody.
Should this product contain a precipitate we recommend microcentrifugation before use.
Testing Data
(Figure A. RPE conjugated rat anti mouse CD4 . Figure B. RPE conjugated rat anti mouse CD4 and A488 conjugated mouse anti mouse CD90 . All experiments performed on red cell lysed murine splenocytes gated on mononuclear cells. Data acquired on the ZE5 cell analyzer.)
Testing Data
(Figure A. RPE conjugated rat anti mouse CD4 . Figure B. RPE conjugated rat anti mouse CD4 and A488 conjugated mouse anti mouse CD90 . All experiments performed on red cell lysed murine splenocytes gated on mononuclear cells. Data acquired on the ZE5 cell analyzer.)
Testing Data
(Figure A. RPE conjugated rat anti mouse CD4 and A647 conjugated mouse IgM isotype control . Figure B. RPE conjugated rat anti mouse CD4 and A647 conjugated mouse anti mouse CD90 . All experiments performed on red cell lysed murine splenocytes gated on mononuclear cells. Data acquired on the ZE5 cell analyzer.)
Testing Data
(Figure A. RPE conjugated rat anti mouse CD4 and A647 conjugated mouse IgM isotype control . Figure B. RPE conjugated rat anti mouse CD4 and A647 conjugated mouse anti mouse CD90 . All experiments performed on red cell lysed murine splenocytes gated on mononuclear cells. Data acquired on the ZE5 cell analyzer.)
Testing Data
(Mouse anti Mouse CD90 antibody, clone F7D5 used for T cell depletion of bone marrow and subsequent evaluation of chimerism by flow cytometry.Image caption:Donor chimerism and alloreactivity. a Percentage donor T cell chimerism in peripheral blood lymphocytes, determined by Thy1.1 (recipient) and Thy1.2 (donor) positivity. b percentage alloreactive CD3+Vbeta6+ T cells. Results are mean +/- SEM from 5 animals in BMT+SPL+SRI and BMT only group and from 4 animals in BMT+SPL+vehicle group. Statistically significant differences are depicted with * (one-tailed p)
Testing Data
(Mouse anti Mouse CD90 antibody, clone F7D5 used for T cell depletion of bone marrow and subsequent evaluation of chimerism by flow cytometry.Image caption:Donor chimerism and alloreactivity. a Percentage donor T cell chimerism in peripheral blood lymphocytes, determined by Thy1.1 (recipient) and Thy1.2 (donor) positivity. b percentage alloreactive CD3+Vbeta6+ T cells. Results are mean +/- SEM from 5 animals in BMT+SPL+SRI and BMT only group and from 4 animals in BMT+SPL+vehicle group. Statistically significant differences are depicted with * (one-tailed p)
The antibody is particularly useful for removal of T lymphocytes from cell populations by complement mediated cytotoxicity (Lake et al. 1979).
Mouse anti Mouse CD90 antibody, clone F7D5 is routinely tested in flow cytometry using mouse thymocytes.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a glycoprotein that is anchored to the cell surface of thymocytes, neuronal and other cells through a glycosyl-phosphatidylinositol moiety. A soluble form of the encoded protein has also been detected in serum and cerebrospinal fluid. The encoded protein undergoes further processing to generate the mature protein which mediates cell-cell interactions to trigger downstream signaling pathways. [provided by RefSeq, Jul 2015]
Uniprot Description
THY1: May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.
Protein type: Motility/polarity/chemotaxis; Membrane protein, GPI anchor; Cell adhesion
Cellular Component: focal adhesion; cell surface; endoplasmic reticulum; dendrite; cytosol; lipid raft; anchored to external side of plasma membrane; growth cone; anchored to plasma membrane; membrane; apical plasma membrane; plasma membrane; myelin sheath; external side of plasma membrane
Molecular Function: integrin binding; enzyme binding; protein kinase binding
Biological Process: focal adhesion formation; negative regulation of T cell receptor signaling pathway; cytoskeleton organization and biogenesis; T cell receptor signaling pathway; cell-cell adhesion; retinal cone cell development; negative regulation of protein kinase activity; negative regulation of axonogenesis; positive regulation of T cell activation; positive regulation of release of sequestered calcium ion into cytosol; angiogenesis; negative regulation of cell migration; positive regulation of GTPase activity
Research Articles on CD90
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Product Notes
The CD90 thy1 (Catalog #AAA225622) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Anti Mouse CD90: RPE reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CD90 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS). Researchers should empirically determine the suitability of the CD90 thy1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD90, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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