Testing Data
(Staining of rat peripheral blood granulocytes probed with Mouse anti Rat CD88 : RPE)
Mouse CD88 Monoclonal Antibody | anti-CD88 antibody
MOUSE ANTI RAT CD88:RPE
Flow Cytometry: Minimum Dilution: Neat; Maximum Dilution: 1/5
Perservative Stabilisers
Fusion Partners
Shelf Life: 18 months from date of reconstitution.
Testing Data
(Staining of rat peripheral blood granulocytes probed with Mouse anti Rat CD88 : RPE)
Testing Data
(Staining of rat peripheral blood granulocytes probed with Mouse anti Rat CD88 : RPE)
NCBI and Uniprot Product Information
NCBI Description
binds complement component 5 and induces Ca+2 release from intracellular stores [RGD, Feb 2006]
Uniprot Description
C5aR: a family 1 G-protein coupled receptor that stimulates the GTPase activity of Gi2. Receptor for the chemotactic and inflammatory complement factor C5a. Stimulates chemotaxis, granule enzyme release and superoxide anion production. Phosphorylated in response to C5a or after stimulation of cells with phorbol esters. Expressed on monocytes, granulocytes, dendritic cells, astrocytes and microglia.
Protein type: Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral
Cellular Component: cell surface; basolateral plasma membrane; apical part of cell; cytoplasmic membrane-bound vesicle; integral to membrane; plasma membrane
Molecular Function: complement component C5a binding; complement component C5a receptor activity; C5a anaphylatoxin receptor activity
Biological Process: neutrophil chemotaxis; organ regeneration; apoptosis; complement receptor mediated signaling pathway; response to lipopolysaccharide; cell proliferation in hindbrain; mRNA transcription from RNA polymerase II promoter; G-protein coupled receptor protein signaling pathway; defense response to Gram-positive bacterium; elevation of cytosolic calcium ion concentration; response to peptidoglycan; negative regulation of neuron apoptosis; inflammatory response; positive regulation of epithelial cell proliferation
Research Articles on CD88
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Product Notes
The CD88 c5ar1 (Catalog #AAA213771) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CD88 can be used in a range of immunoassay formats including, but not limited to, Flow cytometry (FC/FACS). Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul Flow Cytometry: Minimum Dilution: Neat; Maximum Dilution: 1/5. Researchers should empirically determine the suitability of the CD88 c5ar1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD88, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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