Hamster CD81 Monoclonal Antibody | anti-CD81 antibody
CD81 (TAPA-1, Target of anti-Proliferative Antibody-1) (Biotin)
Reactivity
Mouse, Rat, Rodent
Applications
ELISA, Flow Cytometry, Functional Assay, Immunohistochemistry, Immunoprecipitation, Western Blot
Purity
Purified by Protein G Affinity Chromatography
Synonyms
CD81; Monoclonal Antibody; CD81 (TAPA-1; Target of anti-Proliferative Antibody-1) (Biotin); anti-CD81 antibody
Host
Hamster
Reactivity
Mouse, Rat, Rodent
Clonality
Monoclonal
Isotype
IgG1
Clone Number
3H1702
Specificity
Recognizes mouse CD81. Species Crossreactivity: rat
Purity/Purification
Purified by Protein G Affinity Chromatography
Form/Format
Supplied as a liquid in PBS, pH 7.2. Labeled with Biotin.
Applicable Applications for anti-CD81 antibody
ELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
Immunogen
38C13, murine B cell line. Uniprot: P35762
Conjugate
Biotin
Preparation and Storage
Store at -20 degree C.
Product Categories/Family for anti-CD81 antibody
References
1. Clark, K. et al. (2001). PGRL is a major CD81 - associated protein on lymphocytes and distingushes a new family of cell surface proteins. J. Immunol. 167: 5115 - 5121. 2. Maecker, HT et al., Hybridoma 19: 15-22. 3. Conde-Vancells, J. et al. (2010) Candidate biomarkers in exosome-like vesicles purified from rat and mouse urine samples. Proteomics Clin Appl. 4: 416-425. 4. Conde-Vancells, J. et al. (2008) Characterization and comprehensive proteome profiling of exosomes secreted by hepatocytes. J Proteome Res. 7: 5157-66. 5. Takeda, Y. et al. (2008) Double deficiency of tetraspanins CD9 and CD81 alters cell motility and protease production of macrophages and causes chronic obstructive pulmonary disease-like phenotype in mice. J Biol Chem. 283: 26089-97. 6. Suzuki, M. et al. (2009) Tetraspanin CD9 negatively regulates lipopolysaccharide-induced macrophage activation and lung inflammation. J Immunol. 182: 6485-93. 7. Ha, C.T. et al. (2005) Binding of pregnancy-specific glycoprotein 17 to CD9 on macrophages induces secretion of IL-10, IL-6, PGE2, and TGF-beta1. J Leukoc Biol. 77: 948-57. 8. Pan, Q. et al. (2011) Hepatic cell-to-cell transmission of small silencing RNA can extend the therapeutic reach of RNA interference (RNAi). Gut. 61: 1330-9. 9. Jin, Y. et al. (2013) Statins decrease lung inflammation in mice by upregulating tetraspanin CD9 in macrophages. PLoS One. 8: e73706. 10. Royo, F. et al. (2013) Transcriptome of extracellular vesicles released by hepatocytes. PLoS One. 8: e68693. 11. Owens, D.M. and Watt, F.M. (2001) Influence of beta1 integrins on epidermal squamous cell carcinoma formation in a transgenic mouse model: alpha3beta1, but not alpha2beta1, suppresses malignant conversion. Cancer Res. 61: 5248-54.
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Product Notes
The CD81 (Catalog #AAA6248788) is an Antibody produced from Hamster and is intended for research purposes only. The product is available for immediate purchase. The CD81 (TAPA-1, Target of anti-Proliferative Antibody-1) (Biotin) reacts with Mouse, Rat, Rodent and may cross-react with other species as described in the data sheet. AAA Biotech's CD81 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB). Researchers should empirically determine the suitability of the CD81 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD81, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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