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Rat anti-Mouse CD44V6 Monoclonal Antibody | anti-CD44V6 antibody

CD44V6 (HCAM, Homing Cell Adhesion Molecule, Pgp-1, Phagocytic Glycoprotein-1, Hermes Antigen, Lymphocyte Homing Receptor, ECM-III, HUTCH-1) (MaxLight 405)

Gene Names
Cd44; Ly-24; Pgp-1; HERMES; AU023126; AW121933; AW146109
Reactivity
Mouse
Applications
Immunohistochemistry, Western Blot
Purity
Purified IgG.
Synonyms
CD44V6; Monoclonal Antibody; CD44V6 (HCAM; Homing Cell Adhesion Molecule; Pgp-1; Phagocytic Glycoprotein-1; Hermes Antigen; Lymphocyte Homing Receptor; ECM-III; HUTCH-1) (MaxLight 405); anti-CD44V6 antibody
Ordering
For Research Use Only!
Host
Rat
Reactivity
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
3H1351
Specificity
Recognizes an epitope encoded by exon v6 on the variant portion of mouse CD44.
Purity/Purification
Purified IgG.
Form/Format
Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight405.
Applicable Applications for anti-CD44V6 antibody
FLISA, Immunohistochemistry (IHC), Western Blot (WB)
Immunogen
GST-CD44v6 fusion protein.
Conjugate
MaxLight405
Preparation and Storage
Store at 4 degree C. Do Not Freeze.
Product Categories/Family for anti-CD44V6 antibody
References
1. Weiss, J. M. et al. (1997). An essential Role of CD44 variant. Isoforms in Epidermal Langerhans cell and blood dendritic cell function. J. Cell. Biol. 137: 1137-1147.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
39,999 Da
NCBI Official Full Name
CD44 antigen isoform c
NCBI Official Synonym Full Names
CD44 antigen
NCBI Official Symbol
Cd44
NCBI Official Synonym Symbols
Ly-24; Pgp-1; HERMES; AU023126; AW121933; AW146109
NCBI Protein Information
CD44 antigen
UniProt Protein Name
CD44 antigen
UniProt Gene Name
Cd44
UniProt Synonym Gene Names
Ly-24; ECMR-III; Ly-24; PGP-1; PGP-I
UniProt Entry Name
CD44_MOUSE

Uniprot Description

Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis (). Receptor for LGALS9; the interaction enhances binding of SMAD3 to the FOXP3 promoter, leading to up-regulation of FOXP3 expression and increased induced regulatory T (iTreg) cell stability and suppressive function (PubMed:25065622).

Research Articles on CD44V6

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Product Notes

The CD44V6 cd44 (Catalog #AAA6252555) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The CD44V6 (HCAM, Homing Cell Adhesion Molecule, Pgp-1, Phagocytic Glycoprotein-1, Hermes Antigen, Lymphocyte Homing Receptor, ECM-III, HUTCH-1) (MaxLight 405) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CD44V6 can be used in a range of immunoassay formats including, but not limited to, FLISA, Immunohistochemistry (IHC), Western Blot (WB). Researchers should empirically determine the suitability of the CD44V6 cd44 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD44V6, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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