Testing Data
(Mouse spleen cells stained with Rat anti Mouse CD8 alpha:APC and (A) Rat anti Mouse CD283 or (B) rat IgG control. Detection with Goat anti Rat IgG was performed following permeabilisation of the cells with Leucoperm™ prior to incubation with Rat anti Mouse CD283)
Rat anti-Mouse CD283 Monoclonal Antibody | anti-CD283 antibody
CD283 (TLR3) (APC)
Reactivity
Mouse
Applications
Flow Cytometry, Functional Assay
Purity
Purified by protein G affinity chromatography from tissue culture supernatant.
Synonyms
CD283; Monoclonal Antibody; CD283 (TLR3) (APC); anti-CD283 antibody
Host
Rat
Reactivity
Mouse
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
11F8
Specificity
Recognizes mouse CD283.
Purity/Purification
Purified by protein G affinity chromatography from tissue culture supernatant.
Form/Format
Supplied as a liquid in PBS, pH 7.2. Labeled with Allophycocyanin (APC).
Applicable Applications for anti-CD283 antibody
Flow Cytometry (FC/FACS)
Immunogen
Extracellular domain of mouse TLR-3
Conjugate
APC
Preparation and Storage
Store at 4 degree C. Do Not Freeze.
Testing Data
(Mouse spleen cells stained with Rat anti Mouse CD8 alpha:APC and (A) Rat anti Mouse CD283 or (B) rat IgG control. Detection with Goat anti Rat IgG was performed following permeabilisation of the cells with Leucoperm™ prior to incubation with Rat anti Mouse CD283)
Testing Data
(Mouse spleen cells stained with Rat anti Mouse CD8 alpha:APC and (A) Rat anti Mouse CD283 or (B) rat IgG control. Detection with Goat anti Rat IgG was performed following permeabilisation of the cells with Leucoperm™ prior to incubation with Rat anti Mouse CD283)
Testing Data
(Mouse spleen cells stained with Rat anti Mouse CD8 alpha:APC and (A) Rat anti Mouse CD283:FITC or (B) rat IgG control. Staining was performed following permeabilisation of the cells with Leucoperm™ and incubation with Mouse Seroblock FCR.)
Testing Data
(Mouse spleen cells stained with Rat anti Mouse CD8 alpha:APC and (A) Rat anti Mouse CD283:FITC or (B) rat IgG control. Staining was performed following permeabilisation of the cells with Leucoperm™ and incubation with Mouse Seroblock FCR.)
Product Categories/Family for anti-CD283 antibody
References
1. McCartney, S. et al. (2009) Distinct and complementary functions of MDA5 and TLR3 in poly(I:C)- mediated activation of mouse NK cells. J Exp Med. 206: 2967-76. 2. Jelinek, I. et al. (2011) TLR3-specific double-stranded RNA oligonucleotide adjuvants induce dendritic cell cross-presentation, CTL responses, and antiviral protection. J Immunol. 186: 2422-9. 3. Azuma, M. et al. (2012) Cross-priming for antitumor CTL induced by soluble Ag + polyI:C depends on the TICAM-1 pathway in mouse CD11c(+)/CD8alpha(+) dendritic cells. Oncoimmunology. 1: 581-592. 4. McCartney, S.A. et al. (2011) RNA sensor-induced type I IFN prevents diabetes caused by a B cell-tropic virus in mice J Clin Invest. 121: 1497-507.
Similar Products
Product Notes
The CD283 (Catalog #AAA6268435) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The CD283 (TLR3) (APC) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CD283 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS). Researchers should empirically determine the suitability of the CD283 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD283, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
