Testing Data
(Surface Staining of human basophils in allergen-stimulated whole blood (CD203cpos/ SSClow) by Mouse anti Human CD203c:RPE )
Mouse anti-Human CD203c Monoclonal Antibody | anti-CD203c antibody
Mouse Anti Human CD203c: FITC
Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant.
Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant.
Use 4ul of the suggested working dilution to label 1x106 cells in 100ul
This product should be stored undiluted.
This product is photosensitive and should be protected from light.
Testing Data
(Surface Staining of human basophils in allergen-stimulated whole blood (CD203cpos/ SSClow) by Mouse anti Human CD203c:RPE )
Testing Data
(Surface Staining of human basophils in allergen-stimulated whole blood (CD203cpos/ SSClow) by Mouse anti Human CD203c:RPE )
Testing Data
(Surface Staining of activated human basophil by FITC-conjugated anti Human CD63 (clone MEM-259, green) and Mouse anti Human CD203c:RPE ; merged signal yellow. DNA visualized by DAPI (blue))
Testing Data
(Surface Staining of activated human basophil by FITC-conjugated anti Human CD63 (clone MEM-259, green) and Mouse anti Human CD203c:RPE ; merged signal yellow. DNA visualized by DAPI (blue))
Testing Data
(Surface Staining of human basophils in IgE-activated whole blood by Mouse anti Human CD203c:APC )
Testing Data
(Surface Staining of human basophils in IgE-activated whole blood by Mouse anti Human CD203c:APC )
Testing Data
(Surface Staining of human peripheral blood by Mouse anti Human CD203c:FITC )
Testing Data
(Surface Staining of human peripheral blood by Mouse anti Human CD203c:FITC )
CD203c is expressed mainly on activated basophils and mast cells. CD203c is upregulated in response to IgE-receptor cross-linking and is overexpressed on neoplastic mast cells in patients with systemic mastocytosis.
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene belongs to a series of ectoenzymes that are involved in hydrolysis of extracellular nucleotides. These ectoenzymes possess ATPase and ATP pyrophosphatase activities and are type II transmembrane proteins. Expression of the related rat mRNA has been found in a subset of immature glial cells and in the alimentary tract. The corresponding rat protein has been detected in the pancreas, small intestine, colon, and liver. The human mRNA is expressed in glioma cells, prostate, and uterus. Expression of the human protein has been detected in uterus, basophils, and mast cells. Two transcript variants, one protein coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Oct 2015]
Uniprot Description
ENPP3: Cleaves a variety of phosphodiester and phosphosulfate bonds including deoxynucleotides, nucleotide sugars, and NAD. Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
Protein type: Cofactor and Vitamin Metabolism - pantothenate and CoA biosynthesis; Nucleotide Metabolism - purine; EC 3.1.4.1; Phosphodiesterase; Motility/polarity/chemotaxis; Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; Cofactor and Vitamin Metabolism - riboflavin; Carbohydrate Metabolism - starch and sucrose; Membrane protein, integral; EC 3.6.1.9
Chromosomal Location of Human Ortholog: 6q22
Cellular Component: perinuclear region of cytoplasm; integral to plasma membrane
Molecular Function: nucleotide diphosphatase activity; phosphodiesterase I activity; nucleic acid binding; metal ion binding; nucleoside-triphosphate diphosphatase activity; scavenger receptor activity; polysaccharide binding
Biological Process: receptor-mediated endocytosis; nucleoside triphosphate catabolic process; immune response; phosphate metabolic process; inorganic diphosphate transport
Research Articles on CD203c
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Product Notes
The CD203c enpp3 (Catalog #AAA225782) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Anti Human CD203c: FITC reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD203c can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS). FC/FACS: Max. Dilution: Neat Use 4ul of the suggested working dilution to label 1x106 cells in 100ul. Researchers should empirically determine the suitability of the CD203c enpp3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD203c, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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