Rabbit anti-Mouse CD157 Monoclonal Antibody | anti-BST1 antibody
Recombinant Anti-CD157 Antibody, Rabbit Monoclonal
Reactivity
Mouse
Applications
ELISA
Purity
Protein A
Synonyms
CD157; Monoclonal Antibody; Recombinant Anti-CD157 Antibody; Rabbit Monoclonal; CD157/BST1 Antibody; Rabbit MAb; bone marrow stromal cell antigen 1; Anti-114/A10 Antibody; Anti-A530073F09 Antibody; Anti-BP-3 Antibody; Anti-Bp3 Antibody; Anti-Bsta1 Antibody; Anti-CD157 Antibody; Anti-Ly65 Antibody; anti-BST1 antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Monoclonal
Isotype
Rabbit IgG
Clone Number
213
Specificity
Mouse CD157/BST1
Purity/Purification
Protein A
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-BST1 antibody
ELISA (EIA) (Cap)
Application Notes
ELISA (Cap): This antibody will detect Mouse CD157/BST1 in ELISA pair set.
In a sandwich ELISA, it can be used as capture antibody.
In a sandwich ELISA, it can be used as capture antibody.
Antibody Type
Recombinant Antibody
Immunogen
Recombinant Mouse CD157/BST1 Protein
Conjugation
Unconjugated
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD157/BST1 (rM CD157/BST1).
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Related Product Information for anti-BST1 antibody
The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD157, also known as ADP-ribosyl cyclase 2, is an ectoenzyme sharing several characteristics with ADP-ribosyl cyclase CD38. CD157 was originally identified as a bone marrow stromal cell molecule (BST-1) with a glycosylphosphatidylinositol (GPI) anchor to bind to the cell surface. CD157 is prevalently expressed by cells of the myeloid lineage. CD157 could act as a receptor with signal transduction capability. Further, it regulates calcium homeostasis and promotes polarization in neutrophils and mediates superoxide (O2-) production in the human U937 myeloid line.
References
Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.Malavasi F, et al. (2006) CD38 and CD157 as Receptors of the Immune System: A Bridge Between Innate and Adaptive Immunity. Molecular Medicine. 12 (11-12): 334-41.Ortolan E, et al. (2002) CD157, the janus of CD38 but with a unique personality. Cell Biochemistry and Function. 20 (4): 309-22.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
34,616 Da
NCBI Official Full Name
ADP-ribosyl cyclase 2
UniProt Protein Name
ADP-ribosyl cyclase 2
Protein Family
UniProt Gene Name
Bst1
UniProt Synonym Gene Names
Bp-3; Bp3; Ly65; BST-1; cADPr hydrolase 2; Ly-65
UniProt Entry Name
BST1_MOUSE
Uniprot Description
BST1: Synthesizes cyclic ADP-ribose, a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth. Belongs to the ADP-ribosyl cyclase family.
Protein type: EC 3.2.2.6; Hydrolase; Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; Membrane protein, GPI anchor
Cellular Component: membrane; plasma membrane
Molecular Function: transferase activity; phosphorus-oxygen lyase activity; hydrolase activity; NAD+ nucleosidase activity; NAD(P)+ nucleosidase activity
Biological Process: metabolic process; positive regulation of B cell proliferation
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Product Notes
The BST1 bst1 (Catalog #AAA8111378) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Anti-CD157 Antibody, Rabbit Monoclonal reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CD157 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA) (Cap). ELISA (Cap): This antibody will detect Mouse CD157/BST1 in ELISA pair set. In a sandwich ELISA, it can be used as capture antibody. Researchers should empirically determine the suitability of the BST1 bst1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD157, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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