Dilution Information
Mouse anti-Human CD123, IL-3Ra Monoclonal Antibody | anti-CD123 antibody
CD123, IL-3Ra
Reactivity
Human
Synonyms
CD123; IL-3Ra; Monoclonal Antibody; anti-CD123 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1/K
Clone Number
CD123-D3
Form/Format
CD123 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Control
Tonsil, Lymph Node, Kikuchi-Fujimoto Disease
Localization
Membranous
Reactivity Note
Paraffin, Frozen
Preparation and Storage
Store at 2 to 8 degree C in the dark.
Dilution Information
Dilution Information
Immunohistochemistry (IHC)
Immunohistochemistry (IHC)
Related Product Information for anti-CD123 antibody
CD123 is alpha chain of the IL-3 receptor. This 60-70 kDa transmembrane protein, by itself, binds to IL-3 with rather low affinity. However, when associated with CD131 (common beta chain), the protein binds to IL-3 with high affinity. The gene coding for the receptor is located in the pseudoautosomal region of the X and Y chromosomes. The receptor belongs to the Type I cytokine-receptor family and is a heterodimer with a unique alpha chain paired with the common beta (beta c or CDw131) subunit. The CD123 receptor, found on pluripotent progenitor cells, induces tyrosine phosphorylation within the cell and promotes proliferation and differentiation within the hematopoietic cell lines. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, and megakaryocytes.
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Product Notes
The CD123 (Catalog #AAA370017) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CD123, IL-3Ra reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "CD123, IL-3Ra, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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