Testing Data
(Staining of NIH-3T3 cells with Hamster anti Mouse CD121a: Alexa Fluor 647 (MBS212728A647))
Hamster CD121a Monoclonal Antibody | anti-CD121a antibody
HAMSTER ANTI MOUSE CD121a
Purified IgG - liquid
Flow Cytometry: Minimum Dilution: 1/25; Maximum Dilution: 1/100
Preparation
Shelf Life: 18 months from date of despatch.
Testing Data
(Staining of NIH-3T3 cells with Hamster anti Mouse CD121a: Alexa Fluor 647 (MBS212728A647))
Testing Data
(Staining of NIH-3T3 cells with Hamster anti Mouse CD121a: Alexa Fluor 647 (MBS212728A647))
NCBI and Uniprot Product Information
Uniprot Description
IL-1RA: Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex. Belongs to the interleukin-1 receptor family.
Protein type: Receptor, cytokine; Membrane protein, integral; EC 2.7.11.25
Cellular Component: extracellular space; protein complex; cell surface; membrane; axon; postsynaptic density; extracellular region; integral to membrane; plasma membrane; nucleus
Molecular Function: interleukin-1, Type I, activating receptor activity; ionotropic glutamate receptor binding; signal transducer activity; protein binding; protease binding; platelet-derived growth factor receptor binding; interleukin-1 receptor activity
Biological Process: response to radiation; cytokine and chemokine mediated signaling pathway; regulation of inflammatory response; heat acclimation; signal transduction
Research Articles on CD121a
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Product Notes
The CD121a il1r1 (Catalog #AAA212729) is an Antibody produced from Hamster and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CD121a can be used in a range of immunoassay formats including, but not limited to, Flow cytometry (FC/FACS), Immunoprecipitation (IP). Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul. Flow Cytometry: Minimum Dilution: 1/25; Maximum Dilution: 1/100. Researchers should empirically determine the suitability of the CD121a il1r1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD121a, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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