Flow Cytometry (FC/FACS)
(Flow Cytometry evaluation of CD11c expression on dendritic cells using C2262-57D1)
Hamster anti-Mouse CD11c Monoclonal Antibody | anti-CD11c antibody
CD11c (Monocyte/Macrophage, CD11 Antigen-like Family Member C, Complement Component 3 Receptor 4 Subunit, Integrin alphaX, ITGAX, ITAX, Leukocyte Adhesion Glycoprotein p150,95 alpha Chain, Leukocyte Adhesion Receptor p150,95, Leu M5, Leukocyte Surface Ant
Gene Names
Itgax; Cr4; N418; Cd11c; AI449405
Reactivity
Mouse
Applications
Flow Cytometry, Functional Assay, Immunofluorescence, Immunohistochemistry, Immunoprecipitation
Purity
Purified by protein G affinity chromatography from tissue culture supernatant.
Synonyms
CD11c; Monoclonal Antibody; CD11c (Monocyte/Macrophage; CD11 Antigen-like Family Member C; Complement Component 3 Receptor 4 Subunit; Integrin alphaX; ITGAX; ITAX; Leukocyte Adhesion Glycoprotein p150; 95 alpha Chain; Leukocyte Adhesion Receptor p150; 95; Leu M5; Leukocyte Surface Ant; anti-CD11c antibody
Host
Hamster
Reactivity
Mouse
Clonality
Monoclonal
Isotype
IgG
Clone Number
N418
Specificity
Recognizes mouse CD11c.
Purity/Purification
Purified by protein G affinity chromatography from tissue culture supernatant.
Form/Format
Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight750.
Applicable Applications for anti-CD11c antibody
Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP)
Immunogen
Mouse spleen dendritic cells
Conjugate
MaxLight750
Preparation and Storage
Store at 4 degree C. Do Not Freeze.
Flow Cytometry (FC/FACS)
(Flow Cytometry evaluation of CD11c expression on dendritic cells using C2262-57D1)
Flow Cytometry (FC/FACS)
(Flow Cytometry evaluation of CD11c expression on dendritic cells using C2262-57D1)
Testing Data
(Figure A. Alexa647® conjugated rat anti mouse CD11b and FITC conjugated Hamster IgG isotype control. Figure B. Alexa647® conjugated rat anti mouse CD11b andMBS6249487.)
Testing Data
(Figure A. Alexa647® conjugated rat anti mouse CD11b and FITC conjugated Hamster IgG isotype control. Figure B. Alexa647® conjugated rat anti mouse CD11b andMBS6249487.)
Product Categories/Family for anti-CD11c antibody
References
1. Crowley, M. T. et al. (1990) J. Immunol. Methods. 133: 55-66, 2. Metlay, J. P. et al. (1990) J. Exp. Med. 171: 1753-71, 3. Wang, H. et al. (2000) Proc. Natl. Acad. Sci. 97: 847-852. 4. Lundqvist, J. et al. (2010) Infect. Immun. 78: 1924-1930. 5. Beyer, M. et al. (2005) Respir Res. 6: 70. 6. Goupil, M. et al. (2009) Infect Immun. 77: 4136-49. 7. Linehan, S.A. (2005) BMC Immunol. 6:4. 8. Bjorck, P. (2004) J Immunol. 172: 5396-404. 9. Dahlen, E. et al. (1998) Immunol. 160: 3585-93. 10. de Jersey, J. et al. (2002) J Immunol. 169: 6753-9. 11. Dimier-Poisson, I. et al. (2003) Infect Immun. 71: 5254-65. 12. Gonzalez-Juarrero, M. and Orme, I.M. (2001) Infect Immun. 69: 1127-33. 13. Hamada, H. et al. (2002) J Immunol. 168: 57-64. 14. Meng, Q. et al. (2007) Mol Vis. 13: 475-86. 15. Mercier, S. et al. (2002) J Virol. 76: 2899-911. 16. Moos, M.P. et al. (2005) Arterioscler Thromb Vasc Biol. 25: 2386-91. 17. Nunez, R. et al. (1999) Immunol Cell Biol. 77: 153-63. 18. Ponce, L.V. et al. (2005) Kinetoplastid Biol Dis. 4: 2. 19. Zhang, L. et al. (2011) J Mol Endocrinol. Jun 22.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
129,151 Da
NCBI Official Full Name
integrin alpha-X
NCBI Official Synonym Full Names
integrin alpha X
NCBI Official Symbol
Itgax
NCBI Official Synonym Symbols
Cr4; N418; Cd11c; AI449405
NCBI Protein Information
integrin alpha-X; CD11 antigen-like family member C; CD11C (p150) alpha polypeptide; complement receptor 4; integrin aX; leukocyte adhesion glycoprotein p150,95 alpha chain; leukocyte adhesion receptor p150,95
UniProt Protein Name
Integrin alpha-X
UniProt Gene Name
Itgax
UniProt Entry Name
ITAX_MOUSE
Uniprot Description
ITGAX: Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. Belongs to the integrin alpha chain family.
Protein type: Membrane protein, integral; Motility/polarity/chemotaxis
Cellular Component: cell surface; membrane; integral to membrane; integrin complex; external side of plasma membrane
Molecular Function: metal ion binding
Biological Process: integrin-mediated signaling pathway; heterotypic cell-cell adhesion; activated T cell proliferation; cell adhesion; defense response to virus
Research Articles on CD11c
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Product Notes
The CD11c itgax (Catalog #AAA6256521) is an Antibody produced from Hamster and is intended for research purposes only. The product is available for immediate purchase. The CD11c (Monocyte/Macrophage, CD11 Antigen-like Family Member C, Complement Component 3 Receptor 4 Subunit, Integrin alphaX, ITGAX, ITAX, Leukocyte Adhesion Glycoprotein p150,95 alpha Chain, Leukocyte Adhesion Receptor p150,95, Leu M5, Leukocyte Surface Ant reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CD11c can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the CD11c itgax for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD11c, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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