Mouse anti-Chicken CD1.1 Monoclonal Antibody
Mouse Anti-Chicken CD1.1
Reactivity
Chicken
Applications
Flow Cytometry, Immunohistochemistry
Synonyms
CD1.1; Monoclonal Antibody; Mouse Anti-Chicken CD1.1; anti-CD1.1 antibody
Host
Mouse
Reactivity
Chicken
Clonality
Monoclonal
Isotype
Mouse IgG1 kappa
Clone Number
CB3
Specificity
Chicken CD1.1
CD1 molecules, like MHC I and II, play an equally important role in the immune system by presenting lipid, glycolipid and lipopeptide antigen to T and NKT cells1. Chicken CD1 gene is located in the chicken MHC B locus and has an important implication for the primordial MHC gene evolution2. Two proteins have been identified: CD1.1 and CD1.2. Analysis of RNA from blood cells showed that both genes are expressed in Bu-1+ cells (B cells and some macrophages) and CD8a+ cells (some T and NK cells). CD1.2 is expressed in TCR1 + cells (gamma delta cells) but is nearly undetectable in TCR2+ and TCR3+ cells (alpha and Beta T cells)1. Clone CB3 antibody can identify cells of the B cell lineage and recognizes CD1.1 but not CD1.2 on the surface of transfected mammalian cells1.
CD1 molecules, like MHC I and II, play an equally important role in the immune system by presenting lipid, glycolipid and lipopeptide antigen to T and NKT cells1. Chicken CD1 gene is located in the chicken MHC B locus and has an important implication for the primordial MHC gene evolution2. Two proteins have been identified: CD1.1 and CD1.2. Analysis of RNA from blood cells showed that both genes are expressed in Bu-1+ cells (B cells and some macrophages) and CD8a+ cells (some T and NK cells). CD1.2 is expressed in TCR1 + cells (gamma delta cells) but is nearly undetectable in TCR2+ and TCR3+ cells (alpha and Beta T cells)1. Clone CB3 antibody can identify cells of the B cell lineage and recognizes CD1.1 but not CD1.2 on the surface of transfected mammalian cells1.
Form/Format
Purified (UNLB) Antibody
Applicable Applications for anti-CD1.1 antibody
Flow Cytometry; Immunohistochemistry
Application Notes
Flow Cytometry Suggested Dilution: <= 1 ug/10^6 cells
Characterization
To ensure optimal performance, each batch of monoclonal antibody is tested by flow cytometry to conform to characteristics of a standard reference.
Preparation and Storage
The purified (UNLB) antibody is supplied as 0.1 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2- 8 degree C.
References
1. Salomonsen, J., Sørensen, M.R., Marston, D. A., Rogers, S.L., Collen, T., van Hateren, A., Smith, A.L., Beal, R. K., Skjødt, K., and Kaufman, J. 2005 PNAS 102:8668-8673.
2. Miller, M.M., Wang, C., Parisini, E., Coletta, R. D., Goto, R. M., Lee, S. Y., Barral, D. C., Townes, M., Roura-Mir, C., Ford, H.L., Brenner, M. B., and Dascher, C.C. 2005 PNAS 102:8674-8679.
2. Miller, M.M., Wang, C., Parisini, E., Coletta, R. D., Goto, R. M., Lee, S. Y., Barral, D. C., Townes, M., Roura-Mir, C., Ford, H.L., Brenner, M. B., and Dascher, C.C. 2005 PNAS 102:8674-8679.
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Product Notes
The CD1.1 (Catalog #AAA673986) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Anti-Chicken CD1.1 reacts with Chicken and may cross-react with other species as described in the data sheet. AAA Biotech's CD1.1 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry; Immunohistochemistry. Flow Cytometry Suggested Dilution: <= 1 ug/10^6 cells. Researchers should empirically determine the suitability of the CD1.1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD1.1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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