Mouse anti-Human, Mouse CAMK2D Monoclonal Antibody | anti-CAMK2D antibody

CAMK2D (Calcium/Calmodulin-dependent Protein Kinase Type II Subunit delta, CaM Kinase II Subunit delta, CaMK-II Subunit delta, CAMKD) (MaxLight 750)

Cat. Num. AAA6231908

• Gene Names: CAMK2D; CAMKD
• Reactivity: Human, Mouse
• Applications: Immunofluorescence, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: CAMK2D; Monoclonal Antibody; CAMK2D (Calcium/Calmodulin-dependent Protein Kinase Type II Subunit delta; CaM Kinase II Subunit delta; CaMK-II Subunit delta; CAMKD) (MaxLight 750); anti-CAMK2D antibody

• Host: Mouse
• Reactivity: Human, Mouse
• Clonality: Monoclonal
• Isotype: IgG2b
• Clone Number: 1A8
• Specificity: Recognizes human CAMK2D. Species Crossreactivity: mouse
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight750.

• Applicable Applications for anti-CAMK2D antibody: FLISA, Immunofluorescence (IF), Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Partial recombinant corresponding to aa301-410 from human CAMK2D (AAH32784) with GST tag. MW of the GST tag alone is 26kD.
• Immunogen Sequence: KGAILTTMLATRNFSAAKSLLKKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPI
• Conjugate: MaxLight750
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight750 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western Blot detection against Immunogen (37.7kD).)

Western Blot (WB)

(Western Blot analysis of CAMK2D expression in NIH/3T3, using 124290.)

Western Blot (WB)

(Western Blot analysis of CAMK2D expression in transfected 293T cell line using 124290. Lane 1: CAMK2D transfected lysate (54.1kD). Lane 2: Non-transfected lysate.)

Immunofluorescence (IF)

(Immunofluorescence on NIH/3T3 cell using 124290 (10ug/ml).)

Related Product Information for anti-CAMK2D antibody

The multifunctional Ca2+/ calmodulin dependent protein kinase II also known as Calium/calmodulin Kinase (CaMK II) is a well known effector of calcium and calmodulin- mediated functions. It is present in many tissue but it is abundant in brain.CaMKII also required for synaptic plasticity such as Long Term Potentiation (LTP), a cellular model for learning and memory.

Product Categories/Family for anti-CAMK2D antibody

Antibodies; Calmodulin

NCBI and Uniprot Product Information

• NCBI GI #: 21619225
• NCBI GeneID: 817
• Molecular Weight: 54,114 Da
• NCBI Official Full Name: Homo sapiens calcium/calmodulin-dependent protein kinase II delta, mRNA
• NCBI Official Synonym Full Names: calcium/calmodulin dependent protein kinase II delta
• NCBI Official Symbol: CAMK2D
• NCBI Official Synonym Symbols: CAMKD
• NCBI Protein Information: calcium/calmodulin-dependent protein kinase type II subunit delta
• Protein Family: Calcium/calmodulin-dependent protein kinase

NCBI Description

The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a delta chain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Distinct isoforms of this chain have different expression patterns.[provided by RefSeq, Nov 2008]