Mouse anti-Human Calcyclin Binding Protein Monoclonal Antibody | anti-CACYBP antibody
Mouse Anti Human Calcyclin Binding Protein
Gene Names
CACYBP; SIP; GIG5; PNAS-107; S100A6BP
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Purified from mouse ascitic fluids by protein-A affinity chromatography
Synonyms
Calcyclin Binding Protein; Monoclonal Antibody; Mouse Anti Human Calcyclin Binding Protein; CACYBP Antibody; Mouse Anti Human; S100A6BP; S100A6 Binding Protein; GIG5; PNAS-107; RP1-102G20.6; SIP; CACYBP; hCacyBP; Siah-interacting protein; MGC87971; anti-CACYBP antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Clone Number
PAT3G8AT
Purity/Purification
Purified from mouse ascitic fluids by protein-A affinity chromatography
Form/Format
1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide.
Sterile filtered colorless solution.
Sterile filtered colorless solution.
Sequence Length
228
Applicable Applications for anti-CACYBP antibody
ELISA (EIA), Western Blot (WB)
Application Notes
CACYBP antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity.
Ig Subclass
Mouse IgG2a heavy chain and k light chain.
Immunogen
Anti-human CACYBP mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CACYBP protein 1-185 amino acids purified from E Coli.
Preparation and Storage
Storage: For periods up to 1 month store at 4 degree C, for longer periods of time, store at -20 degree C. Prevent freeze thaw cycles.
Stability: 12 months at -20 degree C. 1 month at 4 degree C.
Stability: 12 months at -20 degree C. 1 month at 4 degree C.
Related Product Information for anti-CACYBP antibody
CACYBP (calcyclin binding protein) participates in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. CACYBP acts as a molecular bridge in ubiquitin E3 complexes. CACYBP is involved in the ubiquitin-mediated degradation of beta-catenin.
Product Categories/Family for anti-CACYBP antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
21,228 Da
NCBI Official Full Name
calcyclin binding protein
NCBI Official Synonym Full Names
calcyclin binding protein
NCBI Official Symbol
CACYBP
NCBI Official Synonym Symbols
SIP; GIG5; PNAS-107; S100A6BP
NCBI Protein Information
calcyclin-binding protein
UniProt Protein Name
Calcyclin-binding protein
Protein Family
UniProt Gene Name
CACYBP
UniProt Synonym Gene Names
S100A6BP; SIP; CacyBP; hCacyBP
UniProt Entry Name
CYBP_HUMAN
Uniprot Description
CACYBP: a nuclear/cytoplasmic protein involved in calcium-dependent ubiquitination and proteosomal degradation of target proteins. A possible molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1). Interacts with proteins of the S100 family at physiological calcium concentrations. Component of some large E3 complexes and interacts directly with SIAH1, SIAH2 and SKP1A. Cytoplasmic at low calcium concentrations. In neuroblastoma cells, after a retinoic acid (RA) induction and calcium increase, it localizes in both the nucleus and cytoplasm. The nuclear fraction may be phosphorylated. Two alternatively spliced isoforms have been described.
Protein type: Adaptor/scaffold; Ubiquitin conjugating system
Chromosomal Location of Human Ortholog: 1q24-q25
Cellular Component: beta-catenin destruction complex; cytoplasm; nucleoplasm
Molecular Function: protein binding; protein homodimerization activity
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Product Notes
The CACYBP cacybp (Catalog #AAA140487) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Anti Human Calcyclin Binding Protein reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Calcyclin Binding Protein can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). CACYBP antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Researchers should empirically determine the suitability of the CACYBP cacybp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Calcyclin Binding Protein, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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