Mouse anti-Human C5aR Monoclonal Antibody | anti-C5aR antibody
C5aR, Human, mAb W17/1
Reactivity
Human
Applications
Flow Cytometry, Functional Assay
Synonyms
C5aR; Monoclonal Antibody; Human; mAb W17/1; anti-C5aR antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse IgG1
Form/Format
1 ml (100 ug/ml) 0.2 um filtered antibody solution in PBS, containing 0.1% bovine serum albumin and 0.02 % sodium azide.
For unit size 0.5 mg or larger: PBS only (concentration< 0.5mg/ml)
For unit size 0.5 mg or larger: PBS only (concentration< 0.5mg/ml)
Applicable Applications for anti-C5aR antibody
F, Flow Cytometry (FC/FACS), P
Application Notes
Application Use: For immunohistology and flow cytometry, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10.
Preparation and Storage
Product should be stored at 4 degree C. Under recommended storage conditions, product is stable for one year.
Related Product Information for anti-C5aR antibody
Product Description: The human anaphylatoxin C5a is a 74-residu glycopolypeptide which is generated by proteolytic cleavage of the complement factor C5 in the course of complement activation. A variety of biological effects evoked by C5a could be demonstrated, rendering this molecule an important mediator of inflammation, with granulocytes and macrophages as the main target cells. All cellular responses to C5a are specifically mediated by interactions with the membrane bound C5a receptor, a seven transmembrane GTP-binding-protein-coupled receptor that belongs to the rhodopsin supergene family. The C5a receptor is approximately 45 kDa.
References
1. Opperman, M et al; Probing the human receptor for C5a anaphylatoxin with side-directed antibodies. J Immunol 1993, 151: 3785 2. Opperman, M et al; Antibodies from the myeloid panel that react with the C5a receptor and antagonize C5a biological activity. Schlossman, S.F. (ed.) Leucocyte typing V.O.U.P.: 955-956
3. Werfel, T et al; Binding of anti-C5a receptor (C5aR) antibodies to cells of clinically normal human skin. Schlossman, S.F. (ed.) Leucocyte typing V.O.U.P.: 957-959
4. Opperman, M et al; Plasma clearance of human C5a anaphylatoxin by binding to leucocytes C5a receptors. Immunol 1994, 82: 516
3. Werfel, T et al; Binding of anti-C5a receptor (C5aR) antibodies to cells of clinically normal human skin. Schlossman, S.F. (ed.) Leucocyte typing V.O.U.P.: 957-959
4. Opperman, M et al; Plasma clearance of human C5a anaphylatoxin by binding to leucocytes C5a receptors. Immunol 1994, 82: 516
Similar Products
Product Notes
The C5aR (Catalog #AAA584251) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The C5aR, Human, mAb W17/1 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's C5aR can be used in a range of immunoassay formats including, but not limited to, F, Flow Cytometry (FC/FACS), P. Application Use: For immunohistology and flow cytometry, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10. Researchers should empirically determine the suitability of the C5aR for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "C5aR, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
