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Western Blot (WB) (CRP Antibody western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CRP antibody detected the CRP protein (arrow).)

Mouse anti-Human C-Reactive Protein Monoclonal Antibody | anti-CRP antibody

C-Reactive Protein (CRP, MGC88244, PTX 1, PTX1) (MaxLight 490)

Gene Names
CRP; PTX1
Reactivity
Human
Applications
Western Blot
Purity
Purified by Ammonium Sulfate Precipitation
Synonyms
C-Reactive Protein; Monoclonal Antibody; C-Reactive Protein (CRP; MGC88244; PTX 1; PTX1) (MaxLight 490); anti-CRP antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG3
Clone Number
506CT15.5.3
Purity/Purification
Purified by Ammonium Sulfate Precipitation
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight490.
Applicable Applications for anti-CRP antibody
FLISA, Western Blot (WB)
Immunogen
Purified His-tagged CRP protein (fragment).
Conjugate
MaxLight490
Preparation and Storage
Store at 4 degree C. Do Not Freeze.

Western Blot (WB)

(CRP Antibody western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CRP antibody detected the CRP protein (arrow).)

Western Blot (WB) (CRP Antibody western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CRP antibody detected the CRP protein (arrow).)
Product Categories/Family for anti-CRP antibody
References
Brindle, E., et al. J. Immunol. Methods 362 (1-2), 112-120 (2010) Lim, L.S., et al. Invest. Ophthalmol. Vis. Sci. 51(9):4458-4463(2010) Marott, S.C., et al. J. Am. Coll. Cardiol. 56(10):789-795(2010) Szczesny, G., et al. Arch Orthop Trauma Surg (2010) In press Kuhlenbaeumer, G., et al. Cerebrovasc. Dis. 30(5):476-482(2010)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
25,039 Da
NCBI Official Full Name
C-reactive protein
NCBI Official Synonym Full Names
C-reactive protein, pentraxin-related
NCBI Official Symbol
CRP
NCBI Official Synonym Symbols
PTX1
NCBI Protein Information
C-reactive protein; pentraxin 1
UniProt Protein Name
C-reactive protein
Protein Family
UniProt Gene Name
CRP
UniProt Synonym Gene Names
PTX1
UniProt Entry Name
CRP_HUMAN

NCBI Description

The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. [provided by RefSeq, Sep 2009]

Uniprot Description

CRP: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. Belongs to the pentaxin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 1q23.2

Cellular Component: extracellular space; growth cone; extracellular region; filopodium

Molecular Function: choline binding; protein binding; protein homodimerization activity; low-density lipoprotein receptor binding; complement component C1q binding; cholesterol binding; low-density lipoprotein binding; virion binding; calcium ion binding

Biological Process: protein polymerization; defense response to Gram-positive bacterium; response to ethanol; negative regulation of vasodilation; wound healing; positive regulation of superoxide release; response to lead ion; response to hypoxia; acute-phase response; opsonization; inflammatory response; complement activation, classical pathway; aging

Research Articles on CRP

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Product Notes

The CRP crp (Catalog #AAA6257689) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The C-Reactive Protein (CRP, MGC88244, PTX 1, PTX1) (MaxLight 490) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's C-Reactive Protein can be used in a range of immunoassay formats including, but not limited to, FLISA, Western Blot (WB). Researchers should empirically determine the suitability of the CRP crp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "C-Reactive Protein, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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