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Testing Data

Mouse c-Myc Monoclonal Antibody | anti-c-Myc antibody

c-Myc Antibody

Gene Names
MYC; MRTL; MYCC; c-Myc; bHLHe39
Applications
ELISA, Western Blot
Synonyms
c-Myc; Monoclonal Antibody; c-Myc Antibody; anti-c-Myc antibody
Ordering
For Research Use Only!
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Specificity
Anti-c-Myc recognizes c-Myc and c-Myc tagged fusion proteins.
Form/Format
Each vial contains 100 ug lyophilized IgG.
Sequence Length
454
Applicable Applications for anti-c-Myc antibody
ELISA (EIA), Western Blot (WB-Ti)
Immunogen
Synthetic peptide corresponding to fragment (aa/408-420) c-Myc
Preparation and Storage
The antibody may be stored at room temperature for 1 year at lyophilized form. Additionally, antibody may be stored at 2 degree C to 8 degree C for up to 2-3 weeks without detectable loss of activity after reconstituted in ddH2O. Avoid repeated freeze-thaw cycles of the diluted antibody.

Testing Data

Testing Data
Related Product Information for anti-c-Myc antibody
Purified mouse monoclonal antibody raised against amino acids 408-420 within the C-terminal domain of c-Myc of human origin.
Product Categories/Family for anti-c-Myc antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
50,565 Da
NCBI Official Full Name
myc proto-oncogene protein isoform 1
NCBI Official Synonym Full Names
MYC proto-oncogene, bHLH transcription factor
NCBI Official Symbol
MYC
NCBI Official Synonym Symbols
MRTL; MYCC; c-Myc; bHLHe39
NCBI Protein Information
myc proto-oncogene protein
UniProt Protein Name
Myc proto-oncogene protein
Protein Family
UniProt Gene Name
MYC
UniProt Synonym Gene Names
BHLHE39; bHLHe39

NCBI Description

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]

Uniprot Description

Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis (PubMed:24940000).

Research Articles on c-Myc

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Product Notes

The c-Myc myc (Catalog #AAA853391) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's c-Myc can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB-Ti). Researchers should empirically determine the suitability of the c-Myc myc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "c-Myc, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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