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Western Blot (WB) (Western Blot, human cells)

Mouse c-erbB3 Monoclonal Antibody | anti-c-erbB3 antibody

c-erbB3 (HER 3, ErbB3) (BSA & Azide Free) (MaxLight 550)

Reactivity
Bovine, Human, Mouse, Rat
Applications
ELISA, Immunoprecipitation, Western Blot
Purity
Purified by Protein A Affinity Chromatography
Synonyms
c-erbB3; Monoclonal Antibody; c-erbB3 (HER 3; ErbB3) (BSA & Azide Free) (MaxLight 550); anti-c-erbB3 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Bovine, Human, Mouse, Rat
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
0.N.213
Specificity
Recognizes c-erbB-3/HER-3 at 185kD. Species Crossreactivity: Human, bovine, rat and mouse.
Purity/Purification
Purified by Protein A Affinity Chromatography
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight550.
Applicable Applications for anti-c-erbB3 antibody
ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)
Immunogen
Recombinant rat c-erbB-3/HER-3 oncoprotein expressed in insect cells and purified by metal-chelating chromatography.
Conjugate
MaxLight550
Preparation and Storage
Store at 4 degree C. Do Not Freeze.

Western Blot (WB)

(Western Blot, human cells)

Western Blot (WB) (Western Blot, human cells)
Product Categories/Family for anti-c-erbB3 antibody
References
1. Prigent SA and Lemoine NR. The type I (EGFR-related) family of growth factor receptors and their ligands. Progress in Growth Factor Research, 1992, 4: 1-24. 2. Plowman GD, Culouscou JM, Whitney GS, Green JM, Carlton GW, Foy L, Neubauer MG, and Shoyab M. Proc Natl Acad Sci USA, 1993, 90: 1746-50. 3. Krauss MH, Issing W, Miki T, Popescu NC, and Aaronson SA. Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: Evidence for overexpression in a subset of human mammary tumors. Proc Natl Acad Sci USA, 1989, 86: 9193-7. 4. Plowman GD, Whitney GS, Neubauer MG, Green JM, McDonald VL, Todaro GJ, and Shoyab M. Molecular cloning and expression of an additional epidermal growth factor receptor-related gene. Proc Natl Acad Sci, 1990, 87: 4905-9. 5. Kraus MH, Fedi P, Starks V, Muraro R, Aaronson SA. Demonstration of ligand-dependent signaling by the erbB-3 tyrosine kinase and its constitutive activation in human breast tumor cells. Proc Natl Acad Sci USA, 1993, 90;2900-4. 6. Katoh M, Yazaki Y, Sugimura T, Terada M. c-erbB-3 gene encodes secreted as well as transmembrane receptor tyrosine kinase. Biochem Biophys Res Commun, 1993, 192(3); 1189-97. 7. Fedi P, Pierce JH, Di Fiore PP, Kraus MH. Efficient coupling with phosphatidylinositol 3-kinase, but not phospholipase Cg or GTPase-activating protein, distinguishes erbB-3 signaling from that of other erbB/EGFR family members. Mol Cell Biol, 1994, 14(1); 492-500. 8. Guy PM, Platko JV, Cantley LC, Cerione RA, Carraway KL 3rd. Insect cell-expressed p180erbB3 possesses an impaired tyrosine kinase activity. Proc Natl Acad Sci USA, 1994, 91(17):8132-6. 9. Soltoff SP, Carraway KL 3rd, Prigent SA, Gullick WG, Cantley LC. ErbB3 is involved in activation of phosphatidylinositol 3-kinase by epidermal growth factor. Molecular and Cellular Biology, 1994, 14(6):3550-8. 10. Kim HH, Sierke SL, Koland JG. Epidermal growth factor-dependent association of phosphatidylinositol 3-kinase with the erbB3 gene product. Journal of Biological Chemistry, 1994, 269(40):24747-55.

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Product Notes

The c-erbB3 (Catalog #AAA6267542) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The c-erbB3 (HER 3, ErbB3) (BSA & Azide Free) (MaxLight 550) reacts with Bovine, Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's c-erbB3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB). Researchers should empirically determine the suitability of the c-erbB3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "c-erbB3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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