Immunohistochemistry
(Immunohistochemical staining using BNP antibodyImmunohistochemical analysis of paraffin-embedded human normal myocardium, showing cytoplasmic localization using BNP1 antibody with DAB staining.)
Mouse BNP Monoclonal Antibody | anti-BNP antibody
BNP antibody
Gene Names
nppb; bnp
Applications
ELISA, Immunohistochemistry
Synonyms
BNP; Monoclonal Antibody; BNP antibody; Monoclonal BNP; Anti-BNP; Natriuretic peptide brain type; BNP 32; Brain Natriuretic Peptide; Brain natriuretic peptide 32; NPPB; NPPB protein; Natriuretic peptides B; gamma brain natriuretic peptide; Natriuretic peptide precursor B; anti-BNP antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
8D5B4C11
Form/Format
Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
133
Applicable Applications for anti-BNP antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:10,000
IHC: 1:200-1:1000
IHC: 1:200-1:1000
Biological Significance
Brain natriuretic peptide (BNP) circulates in blood as a peptide hormone with natriuretic, vasodilatory and renin inhibitory properties. BNP is secreted predominantly by the left ventricular myocytes in response to volume expansion and pressure overload. BNP belongs to a family of structurally similar peptide hormones, which includes atrial natriuretic peptide (ANP), BNP, C type natriuretic peptide (CNP) and urodilatin.
Cross-Reactivity
Human
Immunogen
BNP antibody was raised in Mouse using synthetic peptide corresponding to aa (Cys-Phe-Gly-Arg-Lys-Met-Asp-Arg-Ile-Ser-Ser-Ser-Ser) of human BNP, conjugated to KLH as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Immunohistochemistry
(Immunohistochemical staining using BNP antibodyImmunohistochemical analysis of paraffin-embedded human normal myocardium, showing cytoplasmic localization using BNP1 antibody with DAB staining.)
Immunohistochemistry
(Immunohistochemical staining using BNP antibodyImmunohistochemical analysis of paraffin-embedded human normal myocardium, showing cytoplasmic localization using BNP1 antibody with DAB staining.)
Related Product Information for anti-BNP antibody
Mouse monoclonal BNP antibody
Product Categories/Family for anti-BNP antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
14,746 Da
NCBI Official Full Name
brain natriuretic peptide
NCBI Official Symbol
nppb
NCBI Official Synonym Symbols
bnp
NCBI Protein Information
brain natriuretic peptide
UniProt Protein Name
Brain natriuretic peptide
UniProt Gene Name
nppb
UniProt Synonym Gene Names
bnp
UniProt Entry Name
ANFB_TAKRU
Uniprot Description
Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Has a cGMP-stimulating activity ().
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Product Notes
The BNP nppb (Catalog #AAA830218) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's BNP can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). ELISA: 1:10,000 IHC: 1:200-1:1000. Researchers should empirically determine the suitability of the BNP nppb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BNP, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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