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Immunohistochemistry (IHC)
(Amyloid (Abeta) staining on Alzheimer's Disease-Hypothalamus. Tissue pretreated with Citrate, pH 6.0. beta Amyloid antibody was diluted to 1:80. Immunoreactivity is seen as staining on plaque deposits (dark brown).)
Mouse beta Amyloid Monoclonal Antibody
beta Amyloid antibody
Reactivity
Canine, Fish, Human, Monkey, Mouse, Porcine, and rat
Applications
Immunohistochemistry, Western Blot
Synonyms
beta Amyloid; Monoclonal Antibody; beta Amyloid antibody; Monoclonal beta Amyloid; Anti-beta Amyloid; Alzheimer Precursor Protein A4; Ab; Amyloid beta; APP-A4; Abeta; Amyloid Plaque; anti-beta Amyloid antibody
Host
Mouse
Reactivity
Canine, Fish, Human, Monkey, Mouse, Porcine, and rat
Clonality
Monoclonal
Isotype
IgG1
Clone Number
22C11
Form/Format
Liquid in 0.02M PBS, 0.25M NaCl, pH 7.6 with 0.1% sodium azide.
Concentration
1.0 mg/ml (varies by lot)
Applicable Applications for anti-beta Amyloid antibody
Immunohistochemistry (IHC), Western Blot (WB)
Application Notes
IHC: 5-10 ug/ml
WB: 10 ug/ml
WB: 10 ug/ml
Biological Significance
Deposits of amyloid protein in senile plaques near nerve processes are found in the brains of aged humans and cases of Alzheimer's Disease. The principle component of this extracellular amyloid is beta A4, a 4 kDa peptide derived from a larger amyloid precursor protein (APP), which is widely expressed in the brain and body. The creation, transport and function of these proteins is currently an active area of research.
Biohazard Information
This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.
Immunogen
Purified recombinant Alzheimer precursor A4 (Pre A4695) fusion protein.
Preparation and Storage
Store at 4 degree C in undiluted aliquots.
Immunohistochemistry (IHC)
(Amyloid (Abeta) staining on Alzheimer's Disease-Hypothalamus. Tissue pretreated with Citrate, pH 6.0. beta Amyloid antibody was diluted to 1:80. Immunoreactivity is seen as staining on plaque deposits (dark brown).)
Immunohistochemistry (IHC)
(Amyloid (Abeta) staining on Alzheimer's Disease-Hypothalamus. Tissue pretreated with Citrate, pH 6.0. beta Amyloid antibody was diluted to 1:80. Immunoreactivity is seen as staining on plaque deposits (dark brown).)
Immunohistochemistry (IHC)
(Amyloid (Abeta) staining on Alzheimer's Disease-Hypothalamus (left). Tissue pretreated with Citrate, pH 6.0. beta Amyloid antibody diluted to 1:80. Immunoreactivity is seen as cerebral vascular amyloid deposition in the walls of blood vessels (brown). Negative Control staining on Alzheimer's Disease-Hypothalamus (right). Tissue pretreated with Citrate, pH 6.0.)
Immunohistochemistry (IHC)
(Amyloid (Abeta) staining on Alzheimer's Disease-Hypothalamus (left). Tissue pretreated with Citrate, pH 6.0. beta Amyloid antibody diluted to 1:80. Immunoreactivity is seen as cerebral vascular amyloid deposition in the walls of blood vessels (brown). Negative Control staining on Alzheimer's Disease-Hypothalamus (right). Tissue pretreated with Citrate, pH 6.0.)
Immunohistochemistry (IHC)
(Negative Control staining on Alzheimer's Disease-Hypothalamus. Tissue pretreated with Citrate, pH 6.0. Negative Control Reagent, IHC-Select Detection with HRP-DAB.)
Immunohistochemistry (IHC)
(Negative Control staining on Alzheimer's Disease-Hypothalamus. Tissue pretreated with Citrate, pH 6.0. Negative Control Reagent, IHC-Select Detection with HRP-DAB.)
Western Blot (WB)
(APP antibody western blot of endogenous APPs from SH-SY5Y conditioned medium.)
Western Blot (WB)
(APP antibody western blot of endogenous APPs from SH-SY5Y conditioned medium.)
Related Product Information for anti-beta Amyloid antibody
Mouse monoclonal beta Amyloid antibody
Product Categories/Family for anti-beta Amyloid antibody
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Product Notes
The beta Amyloid (Catalog #AAA531316) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The beta Amyloid antibody reacts with Canine, Fish, Human, Monkey, Mouse, Porcine, and rat and may cross-react with other species as described in the data sheet. AAA Biotech's beta Amyloid can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Western Blot (WB). IHC: 5-10 ug/ml WB: 10 ug/ml. Researchers should empirically determine the suitability of the beta Amyloid for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "beta Amyloid, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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