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Mouse anti-Human B-FABP Monoclonal Antibody | anti-B-FABP antibody

B-FABP, Human, mAb 1F5

Gene Names
FABP7; MRG; BLBP; FABPB; B-FABP; LTR2-FABP7
Reactivity
Human
Applications
Flow Cytometry, Functional Assay, Western Blot
Synonyms
B-FABP; Monoclonal Antibody; Human; mAb 1F5; BLBP; FABP7; anti-B-FABP antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse IgG2b
Clone Number
1F5
Form/Format
1 ml (100 ug/ml) 0.2 um filtered antibody solution in PBS, containing 0.01% bovine serum albumin and 0.02% sodium azide.
For unit size 0.5 mg or larger: PBS only (concentration< 0.5mg/ml)
Sequence Length
132
Applicable Applications for anti-B-FABP antibody
Flow Ctometry (FC/FACS), Immuno Assay (IA), Western Blot (WB)
Application Notes
W: A non-reduced and reduced sample treatment and SDS-Page was used. The band size is 18 kDa.
For- flow cytometry and Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. For functional studies, in vitro dilutions have to be optimized in user's experimental setting.
Immunogen
Peptide derived from human B-FABP sequence
Preparation and Storage
Product should be stored at 4 degree C. Under recommended storage conditions, product is stable for at least one year. The exact expiry date is indicated on the label.
Related Product Information for anti-B-FABP antibody
The monoclonal antibody clone 1F5 recognizes human brain fatty acid binding protein (B-FABP, FABP7) of both natural and recombinant origin. The B-FABP protein is derived from the human FABP7 gene. FABPs are small intracellular proteins (~13-14 kDa) with a high degree of tissue specificity that bind long chain fatty acids. They are abundantly present in various cell types and play an important role in the intracellular utilization of fatty acids, transport and metabolism. There are at least nine distinct types of FABP, each showing a specific pattern of tissue expression. Due to its small size, FABP leaks rapidly out of ischemically damaged necrotic cells leading to a rise in serum levels. Ischemically damaged tissues are characterized histologically by absence (or low presence) of FABP facilitating recognition of such areas. B-FABP is localized in the brain and other neural tissues.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
18,829 Da
NCBI Official Full Name
B-FABP
NCBI Official Synonym Full Names
fatty acid binding protein 7, brain
NCBI Official Symbol
FABP7
NCBI Official Synonym Symbols
MRG; BLBP; FABPB; B-FABP; LTR2-FABP7
NCBI Protein Information
fatty acid-binding protein, brain; Hypothetical protein DKFZp547J2313; brain lipid binding protein; brain lipid-binding protein; brain-type fatty acid-binding protein; fatty acid-binding protein 7; mammary-derived growth inhibitor related; mammary-derived growth inhibitor-related
UniProt Protein Name
Fatty acid-binding protein, brain
UniProt Gene Name
FABP7
UniProt Synonym Gene Names
BLBP; FABPB; MRG; BLBP; B-FABP
UniProt Entry Name
FABP7_HUMAN

NCBI Description

The protein encoded by this gene is a brain fatty acid binding protein. Fatty acid binding proteins (FABPs) are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs are thought to play roles in fatty acid uptake, transport, and metabolism. [provided by RefSeq, Jul 2008]

Uniprot Description

FABP7: B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Protein type: Cell cycle regulation; Lipid-binding; Cell development/differentiation

Chromosomal Location of Human Ortholog: 6q22-q23

Cellular Component: cell projection; cell soma; cytoplasm; nucleus

Molecular Function: transporter activity; lipid binding

Biological Process: nervous system development; negative regulation of cell proliferation; epithelial cell proliferation; neurogenesis; prepulse inhibition; transport; cell proliferation in forebrain

Research Articles on B-FABP

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Product Notes

The B-FABP fabp7 (Catalog #AAA584686) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The B-FABP, Human, mAb 1F5 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's B-FABP can be used in a range of immunoassay formats including, but not limited to, Flow Ctometry (FC/FACS), Immuno Assay (IA), Western Blot (WB). W: A non-reduced and reduced sample treatment and SDS-Page was used. The band size is 18 kDa. For- flow cytometry and Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. For functional studies, in vitro dilutions have to be optimized in user's experimental setting. Researchers should empirically determine the suitability of the B-FABP fabp7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "B-FABP, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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