Testing Data
(Human placenta tissue lysate was resolved by electrophoresis, transferred to PVDF membranes and probed with MBS606726 at 1ug/ml. Proteins were visualized using a Goat Anti-Mouse IgG conjugated to HRP and a chemiluminescence detection system. Arrow indicates Achaete Scute homolog 2 (~20kD).)
Mouse anti-Human ASCL2 Monoclonal Antibody | anti-ASCL2 antibody
ASCL2 (Achaete-Scute Complex Homolog 2 (Drosophila), Achaete-scute Homolog 2, ASH2, ASH-2, bHLHa45, BHLHA45, Class A Basic Helix-loop-helix Protein 45, hASH2, HASH2, Mash2, MASH2) (MaxLight 490)
Testing Data
(Human placenta tissue lysate was resolved by electrophoresis, transferred to PVDF membranes and probed with MBS606726 at 1ug/ml. Proteins were visualized using a Goat Anti-Mouse IgG conjugated to HRP and a chemiluminescence detection system. Arrow indicates Achaete Scute homolog 2 (~20kD).)
Testing Data
(Human placenta tissue lysate was resolved by electrophoresis, transferred to PVDF membranes and probed with MBS606726 at 1ug/ml. Proteins were visualized using a Goat Anti-Mouse IgG conjugated to HRP and a chemiluminescence detection system. Arrow indicates Achaete Scute homolog 2 (~20kD).)
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. Involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. [provided by RefSeq, Jul 2008]
Uniprot Description
ASCL2: a basic helix-loop-helix transcription factor, plays an essential role in the maintenance of adult intestinal stem cells
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 11p15.5
Cellular Component: cytoplasm; nucleus
Molecular Function: protein dimerization activity; transcription factor activity
Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; somatic stem cell maintenance; response to hypoxia; negative regulation of transcription from RNA polymerase II promoter; placenta development
Research Articles on ASCL2
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Product Notes
The ASCL2 ascl2 (Catalog #AAA6245675) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The ASCL2 (Achaete-Scute Complex Homolog 2 (Drosophila), Achaete-scute Homolog 2, ASH2, ASH-2, bHLHa45, BHLHA45, Class A Basic Helix-loop-helix Protein 45, hASH2, HASH2, Mash2, MASH2) (MaxLight 490) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ASCL2 can be used in a range of immunoassay formats including, but not limited to, Chromatin Immunoprecipitation (ChIP), Immunocytochemistry (ICC), Immunoprecipitation (IP), Western Blot (WB). Researchers should empirically determine the suitability of the ASCL2 ascl2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ASCL2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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