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Mouse Arrestin 1, beta Monoclonal Antibody | anti-ARRB1 antibody

Arrestin 1, beta (ARRB1, ARB1, ARR1) (MaxLight 550)

Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography
Synonyms
Arrestin 1; beta; Monoclonal Antibody; beta (ARRB1; ARB1; ARR1) (MaxLight 550); anti-ARRB1 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
7G45
Specificity
Reactivity has been confirmed with mouse RAW264.7nuclear extracts and rat PC-12 cell lysates. Based on amino acid sequence homology, reactivity with human is expected.
Purity/Purification
Purified by Protein A Affinity Chromatography
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservatives added. Labeled with MaxLight550.
Applicable Applications for anti-ARRB1 antibody
FLISA, Western Blot (WB)
Immunogen
Synthetic peptide corresponding to the C-terminal region of human beta-arrestin 1, which shares 84% sequence homology with mouse and rat.
Conjugate
MaxLight550
Preparation and Storage
Store at 4 degree C. Do Not Freeze.
Product Categories/Family for anti-ARRB1 antibody
References
1. Parruti G, et al. J Biol Chem 268(13):9753-9761, 1993. 2. Kohout TA, et al. PNAS 98(4):1601-1606, 2001. General References: 1. Lefkowitz, R.J. G protein-coupled receptors. III. New roles for receptor kinases and beta-arrestins in receptor signaling and desensitization. J. Biol. Chem. 273: 18677-18680 (1998). 2. Lin, F.T., et al. Feedback regulation of beta-arrestin1 function by extracellular signal-regulated kinases. J. Biol. Chem. 274: 15971-15974 (1999). 3. Lin, F.T., et al. beta-arrestins regulate mitogenic signaling and clathrin-mediated endocytosis of the insulin-like growth factor I receptor. J Biol Chem. 273: 31640-3 (1998). 4. Miller, W.E., and R.J. Lefkowitz. Expanding roles for beta-arrestins as scaffolds and adapters in GPCR signaling and trafficking. Curr Opin Cell Biol. 13: 139-45 (2001).

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Product Notes

The ARRB1 (Catalog #AAA6259699) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Arrestin 1, beta (ARRB1, ARB1, ARR1) (MaxLight 550) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Arrestin 1, beta can be used in a range of immunoassay formats including, but not limited to, FLISA, Western Blot (WB). Researchers should empirically determine the suitability of the ARRB1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Arrestin 1, beta, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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