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Mouse anti-Mouse Aquaporin 4 (AQP4) Monoclonal Antibody | anti-AQP4 antibody

PE-Linked Monoclonal Antibody to Aquaporin 4 (AQP4)

Gene Names
Aqp4; WCH4
Reactivity
Mouse
Applications
Western Blot, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation
Purity
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Synonyms
Aquaporin 4 (AQP4); Monoclonal Antibody; PE-Linked Monoclonal Antibody to Aquaporin 4 (AQP4); HMIWC2; MIWC; WCH4; Mercurial-insensitive water channel; anti-AQP4 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Mouse
Clonality
Monoclonal
Isotype
IgG
Clone Number
D4
Specificity
The antibody is a Mouse monoclonal antibody raised against AQP4. It has been selected for its ability to recognize AQP4 in immunohistochemical staining and western blotting.
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Form/Format
Liquid
Concentration
>=100ug/ml (varies by lot)
Sequence
AQP4 (Ser177~Ile304)
Sequence Length
323
Applicable Applications for anti-AQP4 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
Conjugation
PE
Cross Reactivity
Mouse
Preparation and Storage
Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months.
Avoid repeated freeze/thaw cycles.

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
aquaporin-4 isoform M1
NCBI Official Synonym Full Names
aquaporin 4
NCBI Official Symbol
Aqp4
NCBI Official Synonym Symbols
WCH4
NCBI Protein Information
aquaporin-4
UniProt Protein Name
Aquaporin-4
Protein Family
UniProt Gene Name
Aqp4
UniProt Synonym Gene Names
AQP-4; MIWC
UniProt Entry Name
AQP4_MOUSE

NCBI Description

This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. This protein is the predominant aquaporin found in brain and has an important role in brain water homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2015]

Uniprot Description

AQP4: a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. The predominant aquaporin found in brain. Two alternatively spliced transcript variants have been described

Protein type: Transporter, aquaporin family; Channel, misc.; Membrane protein, multi-pass; Transporter; Membrane protein, integral

Cellular Component: membrane; basolateral plasma membrane; cell; integral to plasma membrane; cytoplasm; plasma membrane; integral to membrane; intercellular junction

Molecular Function: transporter activity; water channel activity; glycerol channel activity

Biological Process: water homeostasis; glycerol transport; sensory perception of sound; cellular water homeostasis; transport; cellular response to stress; water transport; transmembrane transport

Research Articles on AQP4

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Product Notes

The AQP4 aqp4 (Catalog #AAA2107472) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PE-Linked Monoclonal Antibody to Aquaporin 4 (AQP4) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Aquaporin 4 (AQP4) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the AQP4 aqp4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: AQP4 (Ser177~Il e304). It is sometimes possible for the material contained within the vial of "Aquaporin 4 (AQP4), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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