Mouse Anthrax Protective Antigen Monoclonal Antibody | anti-pxo1_110 antibody
Anthrax Protective Antigen monoclonal antibody (PA6)
Reactivity
Bacillus anthracis
Applications
ELISA, Immunoprecipitation, Western Blot
Purity
Protein G affinity purified.
Synonyms
Anthrax Protective Antigen; Monoclonal Antibody; Anthrax Protective Antigen monoclonal antibody (PA6); anti-pxo1_110 antibody
Host
Mouse
Reactivity
Bacillus anthracis
Clonality
Monoclonal
Isotype
IgG1
Specificity
Recognizes bacteria Anthrax Protective Antigen (PA).
Purity/Purification
Protein G affinity purified.
Form/Format
Liquid. In PBS containing 0.01% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
764
Applicable Applications for anti-pxo1_110 antibody
ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)
Immunogen
Anthrax protective antigen
Source
Purified from hybridoma tissue culture supernatant.
Preparation and Storage
Long term storage: -20°C. Avoid freeze/thaw cycles. Ships on blue ice.
Related Product Information for anti-pxo1_110 antibody
The exotoxin produced by B. anthracis is composed of three proteins: a cell-receptor binding protein known as Protective Antigen (PA), and two enzymes, Edema Factor (EF) and Lethal Factor (LF). An 83 kDa form of PA binds to a cell surface receptor and, upon proteolytic activation to a 63 kDa fragment, heptamerizes to form a membrane channel that mediates the entry of three molecules of LF or EF into the cells. PA and LF form Lethal Toxin, which is the dominant virulence factor produced by B. Anthracis and is the major cause of death in infected animals.
Product Categories/Family for anti-pxo1_110 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
Protective antigen
NCBI Official Symbol
pxo1_110
NCBI Protein Information
pXO1-110
UniProt Protein Name
Protective antigen
UniProt Gene Name
pagA
UniProt Synonym Gene Names
pag; PA; PA83; PA20; PA63
UniProt Entry Name
PAG_BACAN
Uniprot Description
One of the three proteins composing the anthrax toxin, the agent which infects many mammalian species and that may cause death. PA binds to a receptor (ATR) in sensitive eukaryotic cells, thereby facilitating the translocation of the enzymatic toxin components, edema factor and lethal factor, across the target cell membrane. PA associated with LF causes death when injected, PA associated with EF produces edema. PA induces immunity to infection with anthrax.
Research Articles on pxo1_110
Similar Products
Product Notes
The pxo1_110 paga (Catalog #AAA565142) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anthrax Protective Antigen monoclonal antibody (PA6) reacts with Bacillus anthracis and may cross-react with other species as described in the data sheet. AAA Biotech's Anthrax Protective Antigen can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB). Researchers should empirically determine the suitability of the pxo1_110 paga for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Anthrax Protective Antigen, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
