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Mouse Amyloid Beta 1-40 Monoclonal Antibody | anti-Abeta40 antibody

Amyloid Beta 1-40 (Abeta40) Monoclonal Antibody

Applications
Immunoblot, Western Blot, Immunohistochemistry, Immunofluorescence, Immunoprecipitation
Synonyms
Amyloid Beta 1-40; Monoclonal Antibody; Amyloid Beta 1-40 (Abeta40) Monoclonal Antibody; Anti-Amyloid Beta 1-40; anti-Abeta40 antibody
Ordering
For Research Use Only!
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Specificity
This antibody specifically recognizes an epitope within Abetax-40. NOTE: When administered to young Tg2576 mice with minimal Abeta deposition, this antibody reduced Abeta accumulation in the brain.
Form/Format
Purified
Concentration
1.4mg/ml (varies by lot)
Applicable Applications for anti-Abeta40 antibody
Immunoblotting (IB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
Application Notes
Immunoblotting, Immunohistochemistry, Immunofluorescence, Immunoprecipitation, Test at 1-10ug/ml. Sandwich ELISA (works equally well as capture or detection antibody). These are recommended concentrations; end user should determine optimal concentrations for their applications.
Antigen
Synthetic peptide corresponding to Abeta35-40.
Appearance
Clear liquid
Dilution Instructions
Dilute in PBS or medium which is identical to that used in the assay system.
Preparation and Storage
This antibody is stable for at least one (1) year at -20 degree C.
Related Product Information for anti-Abeta40 antibody
Accumulation and aggregation of amyloid beta (Abeta) in the brain is indicated as the trigger of a pathological cascade that causes Alzheimer disease (AD). The highly amyloidogenic 42-amino acid form of Abeta (Abeta42) and aminoterminally truncated forms of Abeta (Abetax-42) are the predominant species of Abeta typically found in diffuse and senile plaques within the AD brain. There is a strong correlation between Abeta40 positivity and mature plaques. In the AD cortex, diffuse plaques, representing the earliest stage of Abeta deposition, are positive for Abeta42, but negative for Abeta40.
Product Categories/Family for anti-Abeta40 antibody

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Product Notes

The Abeta40 (Catalog #AAA190933) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Amyloid Beta 1-40 can be used in a range of immunoassay formats including, but not limited to, Immunoblotting (IB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP). Immunoblotting, Immunohistochemistry, Immunofluorescence, Immunoprecipitation, Test at 1-10ug/ml. Sandwich ELISA (works equally well as capture or detection antibody). These are recommended concentrations; end user should determine optimal concentrations for their applications. Researchers should empirically determine the suitability of the Abeta40 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Amyloid Beta 1-40, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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