Mouse Amyloid Beta 1-16 Monoclonal Antibody | anti-Abeta1-16 antibody
Amyloid Beta 1-16 (Abeta1-16) Monoclonal Antibody
Applications
Immunoblot, Western Blot, Immunohistochemistry, Immunofluorescence, Immunoprecipitation, ELISA
Synonyms
Amyloid Beta 1-16; Monoclonal Antibody; Amyloid Beta 1-16 (Abeta1-16) Monoclonal Antibody; Anti-Amyloid Beta 1-16; anti-Abeta1-16 antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Specificity
This antibody recognizes Abeta1-16 as well as other Abeta peptides: Abeta37, Abeta38, Abeta39, Abeta40, and Abeta42. NOTE: When administered to young Tg2576 mice with minimal Abeta deposition and to older mice with higher Abeta loads, this antibody reduced Abeta accumulation in the brain.
Applicable Applications for anti-Abeta1-16 antibody
Immunoblot (IB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), ELISA (EIA)
Application Notes
Test at 1-10ug/ml in all applications
Antigen
Synthetic peptid corresponding to Abeta1-16.
Dilution Instructions
Dilute in PBS or medium which is identical to that used in the assay system.
Preparation and Storage
This antibody is stable for at least one (1) year at -20 degree C.
Related Product Information for anti-Abeta1-16 antibody
Accumulation and aggregation of amyloid beta (Abeta) in the brain is indicated as the trigger of a pathological cascade that causes Alzheimer disease (AD). There is now compelling evidence that metal binding to Abeta is involved in AD pathogenesis. The amino acid region 1-16 is widely considered as the metal binding domain of Abeta. Unlike copper(II) that prefers the N-terminal amino group as the main binding site, zinc(II) is preferentially placed in the 8-16 amino acidic region of Abeta (1-16).
Product Categories/Family for anti-Abeta1-16 antibody
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Product Notes
The Abeta1-16 (Catalog #AAA190934) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Amyloid Beta 1-16 can be used in a range of immunoassay formats including, but not limited to, Immunoblot (IB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), ELISA (EIA). Test at 1-10ug/ml in all applications. Researchers should empirically determine the suitability of the Abeta1-16 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Amyloid Beta 1-16, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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