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Mouse Amyloid A Monoclonal Antibody | anti-SAA2 antibody

Amyloid A antibody

Applications
ELISA, Immunohistochemistry
Synonyms
Amyloid A; Monoclonal Antibody; Amyloid A antibody; Monoclonal Amyloid A; Anti Amyloid A; anti-SAA2 antibody
Ordering
Host
Mouse
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
Reu-86.2
Specificity
Human Amyloid A
Form/Format
Supplied in liquid form. Dilute immediately before use with PBS or TBS. Contains 0.1% sodium azide.
Sequence Length
122
Applicable Applications for anti-SAA2 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Biological Significance
Amyloids are insoluble fibrous protein aggregates sharing specific structural traits. Abnormal accumulation of amyloid in organs may lead to amyloidosis, and may play a role in various neurodegenerative diseases.
Cross-Reactivity
To be determined by the end user
Immunogen
Amyloid A antibody was raised in mouse using human serum amyloid A (APO SAA) as the immunogen.
Preparation and Storage
Store at 2-8 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Related Product Information for anti-SAA2 antibody
Mouse monoclonal Amyloid A antibody
Product Categories/Family for anti-SAA2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
9,184 Da
NCBI Official Full Name
amyloid A
NCBI Official Synonym Full Names
serum amyloid A2
NCBI Official Symbol
SAA2
NCBI Protein Information
serum amyloid A-2 protein
UniProt Protein Name
Serum amyloid A-2 protein
Protein Family
UniProt Gene Name
SAA2
UniProt Synonym Gene Names
SAA2
UniProt Entry Name
SAA2_HUMAN

Uniprot Description

SAA1: Major acute phase reactant. Apolipoprotein of the HDL complex. Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA1 protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function. Elevated serum SAA1 protein levels may be associated with lung cancer. Belongs to the SAA family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 11p15.1

Cellular Component: extracellular region

Molecular Function: heparin binding; G-protein-coupled receptor binding

Biological Process: receptor-mediated endocytosis; platelet activation; neutrophil chemotaxis; positive regulation of cell adhesion; macrophage chemotaxis; positive regulation of interleukin-1 secretion; elevation of cytosolic calcium ion concentration; regulation of protein secretion; negative regulation of inflammatory response; acute-phase response; innate immune response; lymphocyte chemotaxis; positive regulation of cytokine secretion

Research Articles on SAA2

Similar Products

Product Notes

The SAA2 saa2 (Catalog #AAA533691) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Amyloid A can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the SAA2 saa2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Amyloid A, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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