Western Blot (WB)
(Western BlotA: Sample: Recombinant AREG, Human.)
Mouse Amphiregulin Monoclonal Antibody | anti-AREG antibody
Monoclonal Antibody to Amphiregulin (AREG)
Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.
Avoid repeated freeze/thaw cycles.
Store at 4 degree C for frequent use.
Aliquot and store at -20 degree C for 24 months.
Stability Test:
thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Western Blot (WB)
(Western BlotA: Sample: Recombinant AREG, Human.)
Western Blot (WB)
(Western BlotA: Sample: Recombinant AREG, Human.)
Western Blot (WB)
(Western Blot;Sample:Lane 1: Rat Serum;Lane 2: Rat PlasmaPrimary Ab: 2ug/mL Mouse Anti-Human AREG AntibodySecond Ab: 0.2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (Catalog: MBS2086035 ))
Western Blot (WB)
(Western Blot;Sample:Lane 1: Rat Serum;Lane 2: Rat PlasmaPrimary Ab: 2ug/mL Mouse Anti-Human AREG AntibodySecond Ab: 0.2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (Catalog: MBS2086035 ))
Western Blot (WB)
(Western Blot:Sample: Human MCF7 cells.)
Western Blot (WB)
(Western Blot:Sample: Human MCF7 cells.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P;Samples: Human Liver Tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P;Samples: Human Liver Tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P;Samples: Human Kidney Tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P;Samples: Human Kidney Tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P;Samples: Human Prostate Gland Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P;Samples: Human Prostate Gland Tissue)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions. [provided by RefSeq, Apr 2014]
Uniprot Description
AREG: Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts. Belongs to the amphiregulin family.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 4q13.3
Cellular Component: cell surface; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment membrane; extracellular space; Golgi membrane; integral component of membrane; nucleus
Molecular Function: cytokine activity; epidermal growth factor receptor binding; growth factor activity; protein binding
Biological Process: cell proliferation; cell-cell signaling; COPII vesicle coating; epidermal growth factor receptor signaling pathway; ER to Golgi vesicle-mediated transport; G-protein coupled receptor signaling pathway; glial cell proliferation; negative regulation of osteoblast differentiation; neuron projection development; positive regulation of cell proliferation; positive regulation of DNA replication; positive regulation of peptidyl-tyrosine phosphorylation; response to cAMP; response to estradiol; response to glucocorticoid stimulus; response to hydrogen peroxide; response to peptide hormone
Research Articles on AREG
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Product Notes
The AREG areg (Catalog #AAA2025787) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Monoclonal Antibody to Amphiregulin (AREG) reacts with Homo sapiens (Human) and may cross-react with other species as described in the data sheet. AAA Biotech's Amphiregulin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB); Immunohistochemistry (IHC); Immunocytochemistry (ICC); Immunoprecipitation (IP). Western blotting: 0.5-2ug/mL Immunohistochemistry: 5-20ug/mL Immunocytochemistry: 5-20ug/mL Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the AREG areg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Amphiregulin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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