Mouse anti-Human Aldolase C Monoclonal Antibody | anti-ALDOC antibody

Aldolase C Mouse Monoclonal

Cat. Num. AAA766536

• Gene Names: ALDOC; ALDC
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunofluorescence
• Purity: >=95% as determined by SDS-PAGE; Protein A+G purification
• Synonyms: Aldolase C; Monoclonal Antibody; Aldolase C Mouse Monoclonal; anti-ALDOC antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG1
• Purity/Purification: >=95% as determined by SDS-PAGE; Protein A+G purification
• Form/Format: Liquid
• Sequence Length: 364

• Applicable Applications for anti-ALDOC antibody: ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
• Immunogen: Aldolase C, fructose-bisphosphate
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human liver tissue slide using MBS766536 (ALDOC Antibody) at dilution of 1:200 . heat mediated antigen retrieved with Tris-EDTA buffer (pH9) .)

Western Blot (WB)

(human heart tissue were subjected to SDS PAGE followed by western blot with MBS766536 (ALDOC antibody) at dilution of 1:10000)

NCBI and Uniprot Product Information

• NCBI GI #: 3005698
• NCBI GeneID: 230
• Molecular Weight: 39,456 Da
• NCBI Official Full Name: aldolase C
• NCBI Official Synonym Full Names: aldolase, fructose-bisphosphate C
• NCBI Official Symbol: ALDOC
• NCBI Official Synonym Symbols: ALDC
• NCBI Protein Information: fructose-bisphosphate aldolase C
• UniProt Protein Name: Fructose-bisphosphate aldolase C
• Protein Family: Fructose-bisphosphate aldolase
• UniProt Gene Name: ALDOC
• UniProt Synonym Gene Names: ALDC
• UniProt Entry Name: ALDOC_HUMAN

NCBI Description

This gene encodes a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively. [provided by RefSeq, Jul 2008]

Uniprot Description

ALDOC: a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively. [provided by RefSeq, Jul 2008]

Protein type: EC 4.1.2.13; Lyase; Carbohydrate Metabolism - pentose phosphate pathway; Carbohydrate Metabolism - fructose and mannose; Carbohydrate Metabolism - glycolysis and gluconeogenesis

Chromosomal Location of Human Ortholog: 17cen-q12

Cellular Component: cytoskeleton; cytosol; mitochondrion

Molecular Function: cytoskeletal protein binding; fructose-bisphosphate aldolase activity; protein binding

Biological Process: epithelial cell differentiation; fructose 1,6-bisphosphate metabolic process; fructose metabolic process; gluconeogenesis