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Western Blot (WB) (Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant ALB protein (Right) or empty vector (Left) detected with ALB antibody)

Mouse anti-Human ALB Monoclonal Antibody | anti-ALB antibody

ALB antibody

Gene Names
ALB; FDAH; ANALBA; PRO0883; PRO0903; PRO1341
Reactivity
Human
Applications
Immunofluorescence, Immunohistochemistry, Western Blot
Purity
ALB antibody was purified by affinity chromatography.
Synonyms
ALB; Monoclonal Antibody; ALB antibody; Monoclonal ALB; Anti-ALB; Albumin; Analbuminemia; Bisalbuminemia; Cell growth inhibiting protein 42; Dysalbuminemic hyperthyroxinemia; Growth inhibiting protein 20; HSA; anti-ALB antibody
Ordering
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
4D8
Purity/Purification
ALB antibody was purified by affinity chromatography.
Form/Format
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration
500 ug-1 mg/ml (varies by lot)
Sequence Length
609
Applicable Applications for anti-ALB antibody
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)
Application Notes
IF 1:50
IHC: 1:50
WB: 1:200-500
Biological Significance
ALB (Albumin) refers generally to any protein that is water soluble, which is moderately soluble in concentrated salt solutions, and experiences heat denaturation. They are commonly found in blood plasma, and are unique to other plasma proteins in that they are not glycosylated.
Immunogen
ALB antibody was raised in mouse using a human recombinant protein fragment corresponding to amino acids 19-609 of human ALB (NP_000468) produced in E Coli as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.

Western Blot (WB)

(Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant ALB protein (Right) or empty vector (Left) detected with ALB antibody)

Western Blot (WB) (Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant ALB protein (Right) or empty vector (Left) detected with ALB antibody)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of ALB protein in paraffin embedded Carcinoma of Human liver tissue using ALB antibody)

Immunohistochemistry (IHC) (Immunohistochemical analysis of ALB protein in paraffin embedded Carcinoma of Human liver tissue using ALB antibody)
Related Product Information for anti-ALB antibody
Mouse monoclonal ALB antibody
Product Categories/Family for anti-ALB antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
213
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
45,160 Da
NCBI Official Full Name
serum albumin preproprotein
NCBI Official Synonym Full Names
albumin
NCBI Official Symbol
ALB
NCBI Official Synonym Symbols
FDAH; ANALBA; PRO0883; PRO0903; PRO1341
NCBI Protein Information
serum albumin
UniProt Protein Name
Serum albumin
Protein Family
UniProt Gene Name
ALB
UniProt Entry Name
ALBU_HUMAN

NCBI Description

Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin. [provided by RefSeq, Jul 2008]

Uniprot Description

albumin: Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. Plasma. Belongs to the ALB/AFP/VDB family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted; Carrier

Chromosomal Location of Human Ortholog: 4q13.3

Cellular Component: extracellular space; protein complex; extracellular region; basement membrane; nucleus

Molecular Function: antioxidant activity; toxin binding; protein binding; copper ion binding; enzyme binding; DNA binding; zinc ion binding; chaperone binding; drug binding; oxygen binding; fatty acid binding; pyridoxal phosphate binding

Biological Process: platelet activation; receptor-mediated endocytosis; sodium-independent organic anion transport; maintenance of mitochondrion localization; bile acid metabolic process; hemolysis by symbiont of host red blood cells; lipoprotein metabolic process; cellular response to starvation; response to mercury ion; bile acid and bile salt transport; response to organic substance; retinal homeostasis; platelet degranulation; transport; negative regulation of programmed cell death; blood coagulation; transmembrane transport; positive regulation of circadian sleep/wake cycle, non-REM sleep; response to nutrient; negative regulation of apoptosis

Disease: Analbuminemia; Hyperthyroxinemia, Familial Dysalbuminemic

Research Articles on ALB

Similar Products

Product Notes

The ALB alb (Catalog #AAA831313) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The ALB antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ALB can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB). IF 1:50 IHC: 1:50 WB: 1:200-500. Researchers should empirically determine the suitability of the ALB alb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ALB, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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