Western Blot (WB)
(Western blot detection of AdSS 2 in K562,Rat Brain,C6,3T3,Hela cell lysates using AdSS 2 Rabbit mAb(1:1000 diluted). Predicted band size:50kDa. Observed band size:50kDa.)
Rabbit AdSS 2 Monoclonal Antibody | anti-ADSS antibody
AdSS 2 Rabbit mAb
ICC/IF: 1:20
FC/FACS: 1:20
Western Blot (WB)
(Western blot detection of AdSS 2 in K562,Rat Brain,C6,3T3,Hela cell lysates using AdSS 2 Rabbit mAb(1:1000 diluted). Predicted band size:50kDa. Observed band size:50kDa.)
Western Blot (WB)
(Western blot detection of AdSS 2 in K562,Rat Brain,C6,3T3,Hela cell lysates using AdSS 2 Rabbit mAb(1:1000 diluted). Predicted band size:50kDa. Observed band size:50kDa.)
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes the enzyme adenylosuccinate synthetase which catalyzes the first committed step in the conversion of inosine monophosphate to adenosine monophosphate. A pseudogene of this gene is found on chromosome 17.[provided by RefSeq, Nov 2010]
Uniprot Description
ADSS: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. Belongs to the adenylosuccinate synthetase family.
Protein type: EC 6.3.4.4; Nucleotide Metabolism - purine; Amino Acid Metabolism - alanine, aspartate and glutamate; Ligase
Chromosomal Location of Human Ortholog: 1q44
Cellular Component: cytoplasm; plasma membrane; cytosol
Molecular Function: protein binding; GTP binding; magnesium ion binding; adenylosuccinate synthase activity; phosphate binding
Biological Process: AMP biosynthetic process; response to purine; purine ribonucleoside monophosphate biosynthetic process; nucleobase, nucleoside and nucleotide metabolic process; immune system process; IMP metabolic process; aspartate metabolic process; purine base metabolic process
Research Articles on ADSS
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Product Notes
The ADSS adss (Catalog #AAA4752566) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AdSS 2 Rabbit mAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's AdSS 2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS). WB: 1:1000 ICC/IF: 1:20 FC/FACS: 1:20. Researchers should empirically determine the suitability of the ADSS adss for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AdSS 2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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