Immunohistochemistry (IHC)
(Anti-ADAMTS17 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Mouse anti-Human, Mouse ADAMTS17 Monoclonal Antibody | anti-ADAMTS17 antibody
Mouse Monoclonal [clone 3B7] (IgG1,k) to Human ADAMTS17
Usage: Western Blot (Cell lysate) - positive control A-431. Western Blot (Cell lysate) - positive control NIH/3T3.
Immunohistochemistry (IHC)
(Anti-ADAMTS17 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Immunohistochemistry (IHC)
(Anti-ADAMTS17 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Immunohistochemistry (IHC)
(Anti-ADAMTS17 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Immunohistochemistry (IHC)
(Anti-ADAMTS17 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Western Blot (WB)
(ADAMTS17 monoclonal antibody, clone 3B7 Western blot of ADAMTS17 expression in A-431.)
Western Blot (WB)
(ADAMTS17 monoclonal antibody, clone 3B7 Western blot of ADAMTS17 expression in A-431.)
Western Blot (WB)
(ADAMTS17 monoclonal antibody, clone 3B7. Western blot of ADAMTS17 expression in NIH/3T3.)
Western Blot (WB)
(ADAMTS17 monoclonal antibody, clone 3B7. Western blot of ADAMTS17 expression in NIH/3T3.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has a high sequence similarity to the protein encoded by ADAMTS19, another family member. The function of this protein has not been determined. [provided by RefSeq, Jul 2008]
Uniprot Description
ADAMTS17: Defects in ADAMTS17 are the cause of Weill-Marchesani- like syndrome (WMLS). It is a disorder characterized by many of the key features of Weill-Marchesani syndrome, including lenticular myopia, ectopia lentis, glaucoma, spherophakia and short stature. However, the characteristic brachydactyly or decreased joint flexibility of Weill-Marchesani syndrome are absent. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Protease; Motility/polarity/chemotaxis; Secreted; EC 3.4.24.-
Chromosomal Location of Human Ortholog: 15q24
Cellular Component: proteinaceous extracellular matrix
Molecular Function: zinc ion binding; metalloendopeptidase activity
Biological Process: proteolysis
Disease: Weill-marchesani-like Syndrome
Research Articles on ADAMTS17
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Product Notes
The ADAMTS17 adamts17 (Catalog #AAA246109) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Monoclonal [clone 3B7] (IgG1,k) to Human ADAMTS17 reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ADAMTS17 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA). ELISA, IHC-P (5 ug/ml), WB Usage: Western Blot (Cell lysate) - positive control A-431. Western Blot (Cell lysate) - positive control NIH/3T3. Researchers should empirically determine the suitability of the ADAMTS17 adamts17 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ADAMTS17, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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