Immunohistochemistry (IHC)
(IHC Analysis of Alzheimer disease brain tissue, frontal lobe with 100 ug of antibody from clone C4D10 (after antigen retrieval with Tris- EDTA, pH 9.0 in pressure cooker). The antibody displays specific staining of extracellular plaques and neurofibrillary tangles formed by the Amyloid Beta plaque.)
Mouse ABPP Monoclonal Antibody | anti-ABPP antibody
ABPP antibody
Applications
Immunohistochemistry
Purity
ABPP antibody was purified by affinity chromatography
Synonyms
ABPP; Monoclonal Antibody; ABPP antibody; Monoclonal ABPP; anti-ABPP; Alzheimer disease amyloid protein; Cerebral vascular amyloid peptide (CVAP; APP; Amyloid beta A4 protein APPI; anti-ABPP antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
C4D10
Purity/Purification
ABPP antibody was purified by affinity chromatography
Form/Format
Supplied in PBS buffer, pH 7.2, containing 50% glycerol and 1% BSA.
Concentration
500 ug/ml (varies by lot)
Applicable Applications for anti-ABPP antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 40-150 ug/ml
Biological Significance
Amyloid Beta is a multi-functional peptide of 36-43 amino acids, processed from the Amyloid Precursor Protein. It is most commonly known to be associated with Alzheimer's disease since it is the main component of amyloid plaques found in the brains of the diseased subjects. However, it also plays a role in multiple non-disease activities including protection against metal-induced reactive oxidizing species, modification of cholesterol transport, and potential activity as a transcription factor. It is secreted by platelets into the blood serum and its levels elevate with age.
Cross-Reactivity
Human
Immunogen
ABPP antibody was raised in Mouse using synthetic peptide encoding amino acid residues 1-17 of Amyloid Beta protein as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Immunohistochemistry (IHC)
(IHC Analysis of Alzheimer disease brain tissue, frontal lobe with 100 ug of antibody from clone C4D10 (after antigen retrieval with Tris- EDTA, pH 9.0 in pressure cooker). The antibody displays specific staining of extracellular plaques and neurofibrillary tangles formed by the Amyloid Beta plaque.)
Immunohistochemistry (IHC)
(IHC Analysis of Alzheimer disease brain tissue, frontal lobe with 100 ug of antibody from clone C4D10 (after antigen retrieval with Tris- EDTA, pH 9.0 in pressure cooker). The antibody displays specific staining of extracellular plaques and neurofibrillary tangles formed by the Amyloid Beta plaque.)
Related Product Information for anti-ABPP antibody
Mouse monoclonal ABPP antibody
Product Categories/Family for anti-ABPP antibody
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Product Notes
The ABPP (Catalog #AAA832201) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's ABPP can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 40-150 ug/ml. Researchers should empirically determine the suitability of the ABPP for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ABPP, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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