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Western Blot (Western Blot analysis using ABL1 antibodyWestern Blot showing ABL1 antibody used against truncated GST-ABL1 recombinant protein (1).)

Mouse ABL1 Monoclonal Antibody | anti-ABL1 antibody

ABL1 antibody

Gene Names
ABL1; ABL; JTK7; p150; c-ABL; v-abl; c-ABL1; bcr/abl
Applications
ELISA, Western Blot
Synonyms
ABL1; Monoclonal Antibody; ABL1 antibody; Monoclonal ABL1; Anti-ABL1; V-abl Abelson murine leukemia viral oncogene homolog 1; ABL 1; ABL-1; anti-ABL1 antibody
Ordering
For Research Use Only!
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
7B11D6
Form/Format
Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration
100ul, ascites (varies by lot)
Sequence Length
115
Applicable Applications for anti-ABL1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
ELISA: 1:10,000
WB: 1:500-1:2000
Biological Significance
The ABL1 proto-oncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of ABL1 protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9;22) translocation results in the head-to-tail fusion of the BCR and ABL1 genes, leading to a fusion gene present in many cases of chronic myelogenous leukemia.
Cross-Reactivity
Human
Immunogen
ABL1 antibody was raised in Mouse using a purified recombinant fragment of ABL1(aa577-650) expressed in E Coli as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.

Western Blot

(Western Blot analysis using ABL1 antibodyWestern Blot showing ABL1 antibody used against truncated GST-ABL1 recombinant protein (1).)

Western Blot (Western Blot analysis using ABL1 antibodyWestern Blot showing ABL1 antibody used against truncated GST-ABL1 recombinant protein (1).)
Related Product Information for anti-ABL1 antibody
Mouse monoclonal ABL1 antibody
Product Categories/Family for anti-ABL1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
25
UniProt Accession #
NCBI Official Full Name
ABL1, partial
NCBI Official Synonym Full Names
ABL proto-oncogene 1, non-receptor tyrosine kinase
NCBI Official Symbol
ABL1
NCBI Official Synonym Symbols
ABL; JTK7; p150; c-ABL; v-abl; c-ABL1; bcr/abl
NCBI Protein Information
tyrosine-protein kinase ABL1
UniProt Protein Name
ABL1 protein
Protein Family
UniProt Gene Name
ABL1
UniProt Entry Name
Q13691_HUMAN

NCBI Description

This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function. This gene has been found fused to a variety of translocation partner genes in various leukemias, most notably the t(9;22) translocation that results in a fusion with the 5' end of the breakpoint cluster region gene (BCR; MIM:151410). Alternative splicing of this gene results in two transcript variants, which contain alternative first exons that are spliced to the remaining common exons. [provided by RefSeq, Aug 2014]

Research Articles on ABL1

Similar Products

Product Notes

The ABL1 abl1 (Catalog #AAA831981) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's ABL1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). ELISA: 1:10,000 WB: 1:500-1:2000. Researchers should empirically determine the suitability of the ABL1 abl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ABL1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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