Mouse anti-Human Abeta Monoclonal Antibody
Anti-Human Abeta (aa 17-24), Biotin (clone: 3B7) (Mouse IgG1)
Reactivity
Human
Applications
ELISA
Synonyms
Abeta; Monoclonal Antibody; Anti-Human Abeta (aa 17-24); Biotin (clone: 3B7) (Mouse IgG1); Anti-Human Abeta (aa 17-24) Monoclonal Antibody; anti-Abeta antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
3B7
Specificity
Human Abeta (aa 17-25)
Form/Format
Biotin conjugated IgG buffered in PBS, 0.02% NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml.
Concentration
0.1 mg/ml (varies by lot)
Applicable Applications for anti-Abeta antibody
ELISA (EIA)
Application Notes
This antibody is suitable for use in ELISA (recommended dilution: 1:64K - 1:128K). This antibody has not been tested in other applications.
Hybridoma Production: Fusion Partner
Sp2/0
Hybridoma Production: Immunization
Immunogen: (Iso-L-Asp)-DSGY-EVHHQ-KLVFF-AEDVG-SNKGA-Cys (Abeta 7-30) Donor: Balb/c spleen
Isotype Control
CLCMG115
Preparation and Storage
For all formats, store at 4 degree C. For long term storage (Purified, Biotin, HRPO), aliquot and freeze unused portion at - 20 degree C in volumes appropriate for single usage. Avoid freeze/thaw cycles.
Related Product Information for anti-Abeta antibody
Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in the growing population of elderly people. It is a neurodegenerative disorder characterized by progressive dementia, loss of cognitive abilities, and deposition of fibrillar amyloid proteins as intra-neuronal neurofibrillary tangles, extracellular amyloid plaques and vascular amyloid deposits. The major constituent of these plaques are aggregates of the neurotoxic amyloid-beta (Abeta or Abeta) peptide. This 36-43 amino acid peptide is derived proteolytically from the transmembrane amyloid precursor protein (APP) by sequential secretase processing.
Although the normal function of Abeta is not well understood, several potential activities have been discovered including activation of kinase enzymes, protection against oxidative stress, regulation of cholesterol transport, and anti-microbial activity (potentially associated with Abeta's pro inflammatory activity).
Although the normal function of Abeta is not well understood, several potential activities have been discovered including activation of kinase enzymes, protection against oxidative stress, regulation of cholesterol transport, and anti-microbial activity (potentially associated with Abeta's pro inflammatory activity).
Product Categories/Family for anti-Abeta antibody
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Product Notes
The Abeta (Catalog #AAA520705) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-Human Abeta (aa 17-24), Biotin (clone: 3B7) (Mouse IgG1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Abeta can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). This antibody is suitable for use in ELISA (recommended dilution: 1:64K - 1:128K). This antibody has not been tested in other applications. Researchers should empirically determine the suitability of the Abeta for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Abeta, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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