Western Blot (WB)
(Western blot analysis using 4E-BP1 mouse mAb against truncated 4E-BP1 recombinant protein (1).)
Mouse anti-Human 4E-BP1 Monoclonal Antibody | anti-4E-BP1 antibody
Anti-4E-BP1 Mouse mAb
Gene Names
EIF4EBP1; 4E-BP1
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Synonyms
4E-BP1; Monoclonal Antibody; Anti-4E-BP1 Mouse mAb; BP-1; 4EBP1; PHAS-I; MGC4316; EIF4EBP1; anti-4E-BP1 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
11G12C11
Form/Format
Purified antibody in PBS containing 0.03% sodium azide.
Sequence Length
118
Applicable Applications for anti-4E-BP1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Immunogen
Purified recombinant fragment of 4EBP1 expressed in E Coli.
Western Blot (WB)
(Western blot analysis using 4E-BP1 mouse mAb against truncated 4E-BP1 recombinant protein (1).)
Western Blot (WB)
(Western blot analysis using 4E-BP1 mouse mAb against truncated 4E-BP1 recombinant protein (1).)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human pancreas carcinoma (A), esophagus carcinoma tissue (B) and ovary tumor tissue, showing cytoplasmic and membrane localization using 4E-BP1 mouse mAb with DAB staining.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human pancreas carcinoma (A), esophagus carcinoma tissue (B) and ovary tumor tissue, showing cytoplasmic and membrane localization using 4E-BP1 mouse mAb with DAB staining.)
Related Product Information for anti-4E-BP1 antibody
Entrez Summary: 4E-BP1 (eukaryotic translation Initiation Factor 4E Binding Protein 1), also called ELF4EBP1/BP-1/PHAS-I, which is located on chromosome 8p12, with 118-amino acid protein (about 13kDa). Binding of eIF4EBP1 to eIF4E is reversible and is dependent on the phosphorylation status of eIF4EBP1. Non phosphorylated eIF4EBP1 will bind strongly to eIF4E while (24kDa), the phosphorylated form will not. Akt, TOR, MAP kinase, S6 kinase, and Cdc2 are known kinases capable of inactivating eIF4EBP1 binding to eIF4E by phosphorylating either threonines 35, 45, 69 or serine 64. Although, not all phosphorylation events equally block the eIF4EBP1-eIF4E interaction.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
12,489 Da
NCBI Official Full Name
4E-BP1
NCBI Official Symbol
EIF4EBP1
NCBI Official Synonym Symbols
4E-BP1
NCBI Protein Information
eukaryotic translation initiation factor 4E-binding protein 1
UniProt Protein Name
4E-BP1
UniProt Gene Name
4E-BP1
Research Articles on 4E-BP1
Similar Products
Product Notes
The 4E-BP1 4e-bp1 (Catalog #AAA475720) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-4E-BP1 Mouse mAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's 4E-BP1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the 4E-BP1 4e-bp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "4E-BP1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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