Mouse anti-Human 14-3-3 eta/YWHAH Monoclonal Antibody | anti-14-3-3 eta/YWHAH antibody

Mouse anti Human 14-3-3 eta/YWHAH Monoclonal Antibody

Cat. Num. AAA2543489

• Gene Names: YWHAH; YWHA1
• Reactivity: Human
• Applications: Western Blot, ELISA, Immunoprecipitation
• Synonyms: 14-3-3 eta/YWHAH; Monoclonal Antibody; Mouse anti Human 14-3-3 eta/YWHAH Monoclonal Antibody; anti-14-3-3 eta/YWHAH antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG1
• Sequence Length: 246

• Applicable Applications for anti-14-3-3 eta/YWHAH antibody: Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
• Application Notes: WB: 0.5-2 mug/mL; ELISA: 0.5-1 mug/mL. This antibody can be used at 0.5-1 mug/mL with the appropriate secondary reagents to detect Human YWHAH. The detection limit for Human YWHAH is approximately 0.078 ng/well.; IP: 2-8 mug/mg of lysate
• Immunogen: Recombinant Human 14-3-3 eta/YWHAH protein
• Buffer: 0.2 mum filtered solution in PBS with 5% trehalose
• Preparation and Storage: This antibody can be stored at 2 degree C- 8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

NCBI and Uniprot Product Information

• NCBI GI #: 4507951
• NCBI GeneID: 7533
• NCBI GenBank Nucleotide #: NM_003405.3
• Molecular Weight: 28,219 Da
• NCBI Official Full Name: 14-3-3 protein eta
• NCBI Official Synonym Full Names: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
• NCBI Official Symbol: YWHAH
• NCBI Official Synonym Symbols: YWHA1
• NCBI Protein Information: 14-3-3 protein eta
• UniProt Protein Name: 14-3-3 protein eta
• UniProt Gene Name: YWHAH
• UniProt Synonym Gene Names: YWHA1
• UniProt Entry Name: 1433F_HUMAN

NCBI Description

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder. [provided by RefSeq, Jun 2009]

Uniprot Description

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.