Monkey Prolactin receptor (PRLR) ELISA Kit | PRLR elisa kit
Monkey Prolactin receptor (PRLR) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011]
Uniprot Description
PRLR: receptor for the anterior pituitary hormone prolactin and placental lactogen I and II. Interacts with Cyclophilin A, differentially regulating various signaling pathways from the PrlR. Prolactin signaling is attenuated by threonine and tyrosine phosphorylation. Two alternative splice isoforms have been identified.
Protein type: Receptor, cytokine; Membrane protein, integral
Chromosomal Location of Human Ortholog: 5p13.2
Cellular Component: cell surface; integral to membrane; plasma membrane; extracellular region
Molecular Function: protein binding; protein homodimerization activity; ornithine decarboxylase activator activity; metal ion binding; peptide hormone binding; prolactin receptor activity
Biological Process: lactation; regulation of cell adhesion; cell surface receptor linked signal transduction; transmembrane receptor protein tyrosine kinase activation (dimerization); T cell activation; regulation of epithelial cell differentiation; tyrosine phosphorylation of JAK2 protein; steroid biosynthetic process; embryo implantation; negative regulation of apoptosis
Disease: Multiple Fibroadenomas Of The Breast; Hyperprolactinemia
Research Articles on PRLR
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Product Notes
The Monkey PRLR prlr (Catalog #AAA7253326) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7253326 ELISA Kit recognizes Monkey PRLR. It is sometimes possible for the material contained within the vial of "Prolactin receptor (PRLR), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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