Typical Testing Data/Standard Curve (for reference only)
Mouse CDK-activating kinase assembly factor MAT1 ELISA Kit | Mnat1 elisa kit
Mouse CDK-activating kinase assembly factor MAT1 ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
Uniprot Description
MNAT1: Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminus domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II.
Protein type: Cell cycle regulation; Ubiquitin ligase; Ubiquitin conjugating system; Nuclear receptor co-regulator
Cellular Component: cytoplasm; holo TFIIH complex; nucleoplasm; nucleus
Molecular Function: DNA-dependent ATPase activity; metal ion binding; protein binding; protein N-terminus binding; RNA polymerase subunit kinase activity; zinc ion binding
Biological Process: adult heart development; cell cycle; DNA repair; G1/S transition of mitotic cell cycle; negative regulation of apoptosis; positive regulation of smooth muscle cell proliferation; positive regulation of transcription from RNA polymerase II promoter; protein amino acid phosphorylation; regulation of cyclin-dependent protein kinase activity; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; response to calcium ion; transcription from RNA polymerase II promoter; transcription, DNA-dependent; ventricular system development
Research Articles on Mnat1
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Product Notes
The Mouse Mnat1 mnat1 (Catalog #AAA2882259) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2882259 ELISA Kit recognizes Mouse Mnat1. It is sometimes possible for the material contained within the vial of "CDK-activating kinase assembly factor MAT1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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