Matrilysin Recombinant Protein | MMP7 recombinant protein

Matrilysin protein

Cat. Num. AAA5303962

• Gene Names: MMP7; MMP-7; MPSL1; PUMP-1
• Applications: ELISA, SDS-Page, Western Blot
• Purity: > 90% pure
• Synonyms: Matrilysin; Matrilysin protein; Matrin protein; Matrix metalloproteinase 7 protein; MMP 7 protein; Pump 1 protease protein; Uterine metalloproteinase protein; MMP7 recombinant protein

• Host: Human
• Purity/Purification: > 90% pure
• Form/Format: Supplied in liquid form in 6M guanidine hydrochloride and 20mM Tris buffer
• Sequence Length: 267

• Applicable Applications for MMP7 recombinant protein: ELISA (EIA), SDS-PAGE, Western Blot (WB)
• Protein Type: Recombinant
• Biological Significance: Matrilysin degrades casein, gelatins of types I, III, IV, and V, as well as fibronectin. Matrilysin activates procollagenase.
• Expression System: E Coli
• Preparation and Storage: Store at 4 degree C in a working aliquot for 1 week. For long term storage, aliquot and freeze at -20 to -80 degree C, avoid repeat freeze/thaw cycles

Western Blot (WB)

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Related Product Information for MMP7 recombinant protein

Purified recombinant Matrilysin protein

Product Categories/Family for MMP7 recombinant protein

Cell Biology

NCBI and Uniprot Product Information

• NCBI GI #: 4505219
• NCBI GeneID: 4316
• NCBI Accession #: NP_002414.1
• NCBI GenBank Nucleotide #: NM_002423.3
• Molecular Weight: 46 kDa
• NCBI Official Full Name: matrilysin preproprotein
• NCBI Official Synonym Full Names: matrix metallopeptidase 7
• NCBI Official Symbol: MMP7
• NCBI Official Synonym Symbols: MMP-7; MPSL1; PUMP-1
• NCBI Protein Information: matrilysin
• UniProt Protein Name: Matrilysin
• Protein Family: Matrilysin
• UniProt Gene Name: MMP7
• UniProt Synonym Gene Names: MPSL1; PUMP1; MMP-7
• UniProt Entry Name: MMP7_HUMAN

NCBI Description

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]

Uniprot Description

MMP7: Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase. Belongs to the peptidase M10A family.

Protein type: Secreted; Secreted, signal peptide; EC 3.4.24.23; Protease

Chromosomal Location of Human Ortholog: 11q22.2

Cellular Component: extracellular space; proteinaceous extracellular matrix; extracellular region

Molecular Function: zinc ion binding; metalloendopeptidase activity

Biological Process: response to drug; collagen catabolic process; extracellular matrix disassembly; extracellular matrix organization and biogenesis; defense response to Gram-positive bacterium; antibacterial peptide biosynthetic process; defense response to Gram-negative bacterium; proteolysis; antibacterial peptide secretion; regulation of cell proliferation