Mouse Williams-Beuren syndrome chromosomal region 14 protein ELISA Kit | MLXIPL elisa kit
Mouse Williams-Beuren syndrome chromosomal region 14 protein (MLXIPL) ELISA Kit
Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate MLXIPL in Mouse serum, plasma. An antibody specific for MLXIPL has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any MLXIPL present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for MLXIPL is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of MLXIPL bound in the initial step. The color development is stopped and the intensity of the color is measured.
NCBI and Uniprot Product Information
Uniprot Description
ChREBP: Transcriptional repressor. Binds to the canonical and non-canonical E box sequences 5'-CACGTG-3'. Binds DNA as a heterodimer with TCFL4/MLX. Expressed in liver, heart, kidney, cerebellum and intestinal tissues. 6 isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription factor
Chromosomal Location of Human Ortholog: 5|5 G2
Cellular Component: cytoplasm; cytosol; nucleus; transcription factor complex
Molecular Function: DNA binding; DNA binding transcription factor activity; protein binding; protein dimerization activity; protein heterodimerization activity; protein kinase binding; sequence-specific DNA binding; transcription factor binding
Biological Process: cellular response to glucose stimulus; fatty acid homeostasis; glucose homeostasis; glucose mediated signaling; negative regulation of cell cycle arrest; negative regulation of oxidative phosphorylation; negative regulation of peptidyl-serine phosphorylation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of cell proliferation; positive regulation of fatty acid biosynthetic process; positive regulation of glycolysis; positive regulation of lipid biosynthetic process; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-templated; regulation of energy homeostasis; regulation of glycolysis; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-templated; response to glucose stimulus; transcription, DNA-dependent
Research Articles on MLXIPL
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Product Notes
The Mouse MLXIPL mlxipl (Catalog #AAA280478) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA280478 ELISA Kit recognizes Mouse MLXIPL. It is sometimes possible for the material contained within the vial of "Williams-Beuren syndrome chromosomal region 14 protein, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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