Mouse myeloid/lymphoid or mixed-lineage leukemia 2 ELISA Kit | MLL2 elisa kit
Mouse Histone-lysine N-methyltransferase MLL2, MLL2 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
MLL4: Histone methyltransferase. Methylates 'Lys-4' of histone H3 (H3K4me). H3K4me represents a specific tag for epigenetic transcriptional activation. Acts as a coactivator for estrogen receptor by being recruited by ESR1, thereby activating transcription. Defects in MLL2 are the cause of Kabuki syndrome type 1 (KABUK1). A congenital mental retardation syndrome with additional features, including postnatal dwarfism, a peculiar facies characterized by long palpebral fissures with eversion of the lateral third of the lower eyelids, a broad and depressed nasal tip, large prominent earlobes, a cleft or high-arched palate, scoliosis, short fifth finger, persistence of fingerpads, radiographic abnormalities of the vertebrae, hands, and hip joints, and recurrent otitis media in infancy. Belongs to the histone-lysine methyltransferase family. TRX/MLL subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 2.1.1.43; Nuclear receptor co-regulator; Methyltransferase, protein lysine; Transcription regulation; Methyltransferase
Cellular Component: histone methyltransferase complex; nucleus
Molecular Function: transferase activity; methyltransferase activity; zinc ion binding; metal ion binding; histone-lysine N-methyltransferase activity
Biological Process: oogenesis; methylation; oocyte growth; transcription, DNA-dependent; in utero embryonic development; chromatin silencing; histone H3-K4 methylation; positive regulation of estrogen receptor signaling pathway; chromatin modification; regulation of transcription, DNA-dependent; response to estrogen stimulus; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter
Research Articles on MLL2
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Product Notes
The Mouse MLL2 kmt2d (Catalog #AAA9323703) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9323703 ELISA Kit recognizes Mouse MLL2. It is sometimes possible for the material contained within the vial of "myeloid/lymphoid or mixed-lineage leukemia 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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