Probable E3 ubiquitin-protein ligase makorin-2 (mkrn2) Recombinant Protein | mkrn2 recombinant protein
Recombinant Xenopus tropicalis Probable E3 ubiquitin-protein ligase makorin-2 (mkrn2)
Gene Names
mkrn2; rnf62; Makorin-2
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Probable E3 ubiquitin-protein ligase makorin-2 (mkrn2); Recombinant Xenopus tropicalis Probable E3 ubiquitin-protein ligase makorin-2 (mkrn2); mkrn2 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-418, Full length protein
Sequence
MNTKHVTCRYFLHGVCREGGRCLFSHDLATSKPSTVCRFYQRGQCAYGARCRYDHVKPCNGSVFYPPQEMAPAPLESTPPLLPTQEAAAPVTKSAPQRREKKSVVLRDRDLCGASVEKAHPDPALRPGCAADPPVSELEAKPHSYLEAICTGLDETPIPSAYPDAPQQLCPFAQAGGCHYGESCPYIHGNVCEICGLQVLHPYDQEQRGHHEKLCMANFERDMERAFAFQASEGKVCSICMERVYDKQSPSERRFGILSNCHHTYCLACIRQWRCARQFENPVIKSCPECRVISEFVIPSAYWVEDQSKKFELIEAFKQGMGKKACKYFDQGRGTCPFGGKCLYLHAYPDGTRAEPEKPRKQLGSEGTVRFLNSVRLWDFIEEREQRNLPDAEDEVAELGELFMHLSGVGEEPPAASN
Sequence Length
418
Species
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
46,881 Da
NCBI Official Full Name
probable E3 ubiquitin-protein ligase makorin-2
NCBI Official Synonym Full Names
makorin ring finger protein 2
NCBI Official Symbol
mkrn2
NCBI Official Synonym Symbols
rnf62; Makorin-2
NCBI Protein Information
probable E3 ubiquitin-protein ligase makorin-2
UniProt Protein Name
Probable E3 ubiquitin-protein ligase makorin-2
Protein Family
UniProt Gene Name
mkrn2
Uniprot Description
E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Inhibits neurogenesis and axis formation during embryonic development by modulating the phosphatidylinositol 3-kinase (PI3K) pathway. Acts downstream of PI3K and akt1 to up-regulate gsk3b mRNA expression.
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Product Notes
The mkrn2 mkrn2 (Catalog #AAA1322659) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-418, Full length protein. The amino acid sequence is listed below: MNTKHVTCRY FLHGVCREGG RCLFSHDLAT SKPSTVCRFY QRGQCAYGAR CRYDHVKPCN GSVFYPPQEM APAPLESTPP LLPTQEAAAP VTKSAPQRRE KKSVVLRDRD LCGASVEKAH PDPALRPGCA ADPPVSELEA KPHSYLEAIC TGLDETPIPS AYPDAPQQLC PFAQAGGCHY GESCPYIHGN VCEICGLQVL HPYDQEQRGH HEKLCMANFE RDMERAFAFQ ASEGKVCSIC MERVYDKQSP SERRFGILSN CHHTYCLACI RQWRCARQFE NPVIKSCPEC RVISEFVIPS AYWVEDQSKK FELIEAFKQG MGKKACKYFD QGRGTCPFGG KCLYLHAYPD GTRAEPEKPR KQLGSEGTVR FLNSVRLWDF IEEREQRNLP DAEDEVAELG ELFMHLSGVG EEPPAASN. It is sometimes possible for the material contained within the vial of "Probable E3 ubiquitin-protein ligase makorin-2 (mkrn2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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