Mitotic chromosome and X-chromosome-associated protein mix-1 (mix-1) Recombinant Protein | mix-1 recombinant protein
Recombinant Caenorhabditis elegans Mitotic chromosome and X-chromosome-associated protein mix-1 (mix-1), partial
NCBI and Uniprot Product Information
Uniprot Description
Essential protein required for both chromosome condensation and segregation and X-chromosome dosage compensation depending on its binding partners (PubMed:9458050, PubMed:11914278, PubMed:19119011, PubMed:18198337, PubMed:19781752). Central component of the condensin I complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes (PubMed:11914278, PubMed:18198337, PubMed:19119011). The condensin complex introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases (PubMed:11914278). Converts nicked DNA into positive knotted forms in the presence of type II topoisomerases (). Central component of the condensin II complex, a complex that seems to play a role in prophase chromosome condensation and organization (PubMed:19119011, PubMed:15557118). Both the condensin complex I and II play a role in meiotic and mitotic chromosome segregation (PubMed:11914278, PubMed:19119011, PubMed:15557118). Plays a role in robust cytokinesis upon the presence of chromatin obstructions (PubMed:23684975). Also a member of the condensin I-like dosage compensation complex that associates specifically with hermaphrodite X chromosomes to reduce their gene transcription during interphase (PubMed:9458050, PubMed:19119011, PubMed:18198337, PubMed:19781752).
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Product Notes
The mix-1 mix-1 (Catalog #AAA1296557) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Mitotic chromosome and X-chromosome-associated protein mix-1 (mix-1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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